Results 31 to 40 of about 5,116,032 (159)
Lavenders include some 28 species of evergreen aromatic shrubs and subshrubs belonging to the mint family, the Lamiaceae. They occur mainly around the Mediterranean and their flowers range from pink to purple and white.
O. Kobets +3 more
doaj +1 more source
ABSTRACT Musculocontractural Ehlers‐Danlos syndrome (EDS) caused by pathogenic variants in the carbohydrate sulfotransferase 14 gene (CHST14) (mcEDS‐CHST14) is an autosomal recessive connective tissue disorder characterized by congenital malformations including specific craniofacial features, congenital multiple contractures, and progressive fragility ...
Shuji Mizumoto +7 more
wiley +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source
Molecular Evolution and Gene Diversity of Dermatan Sulfate Sulfotransferases in Ascidians
ABSTRACT Ascidians (Chordata, Tunicata) are model organisms for studying molecules, particularly sulfated glycosaminoglycans (GAGs), due to their phylogenetic proximity to vertebrates and unique GAG variants. Over‐sulfated dermatan sulfate (DS) contributes to proteoglycan diversity and cellular processes in metazoans.
Vanessa de Sousa Rizzo‐Valente +1 more
wiley +1 more source
Heparanase 1 (HPSE1) and Heparanase 2 (HPSE2) exhibit opposing expression patterns and functions in pathological contexts, such as cancer. Here, we describe their specific expression in immune cells and their implications in skin diseases. Although they are structurally similar and considered to be ‘cousins’, we found no common ancestor and that HPSE2 ...
Elham Vahdatahar +12 more
wiley +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
This study investigates the phytochemical composition and biopharmacological potential of the extracts from three Hypericum species (H. scabrum, H. lysimachioides, and H. uniglandulosum) from Turkey. The results indicate significant therapeutic potential for these extracts, supporting their development as natural agents against oxidative stress ...
Muammer Bahsi +12 more
wiley +1 more source
Alveolar Glycocalyces During Health and Critical Illness
ABSTRACT The alveolus, the functional unit of the lung, is comprised of closely approximated alveolar epithelial and endothelial cells, across which gas exchange occurs. This alveolar septum also includes two substantial, intraluminal extracellular matrices: the alveolar epithelial and endothelial glycocalyces.
Yimu Yang, Eric P. Schmidt
wiley +1 more source
Disaccharide Analysis of Glycosaminoglycans From Twenty‐Four Organs of Young and Aged Mice
ABSTRACT Glycosaminoglycans (GAGs) are abundant negatively charged polysaccharides ubiquitously expressed in mammalian organs, having essential biological functions in development and homeostasis. It has been scarcely reported that GAG structures are changed in aged and diseased human organs; however, an overall landscape of GAGs in individual organs ...
Emil Tykesson +3 more
wiley +1 more source

