FEBS Letters, Volume 599, Issue 15, Page 2190-2200, August 2025.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
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How Sweet Are Our Gut Beneficial Bacteria? A Focus on Protein Glycosylation in Lactobacillus [PDF]
, 2018 Protein glycosylation is emerging as an important feature in bacteria. Protein glycosylation systems have been reported and studied in many pathogenic bacteria, revealing an important diversity of glycan structures and pathways within and between ...
Dimitrios Latousakis +2 more
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Food Science &Nutrition, Volume 13, Issue 4, April 2025.This study investigates the phytochemical composition and biopharmacological potential of the extracts from three Hypericum species (H. scabrum, H. lysimachioides, and H. uniglandulosum) from Turkey. The results indicate significant therapeutic potential for these extracts, supporting their development as natural agents against oxidative stress ...
Muammer Bahsi +12 more
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Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type. [PDF]
, 2017 Amyloid aggregates found in the brain of patients with neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are thought to spread to increasingly larger areas of the brain through a prion-like seeding mechanism.
Esko, Jeffrey D +5 more
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Alveolar Glycocalyces During Health and Critical Illness
Proteoglycan Research, Volume 3, Issue 1, January-March 2025.ABSTRACT The alveolus, the functional unit of the lung, is comprised of closely approximated alveolar epithelial and endothelial cells, across which gas exchange occurs. This alveolar septum also includes two substantial, intraluminal extracellular matrices: the alveolar epithelial and endothelial glycocalyces.
Yimu Yang, Eric P. Schmidt
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Extraction and structural study of hemicellulose B from tall fescue (Festuca arundinacea) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]
, 1971 1.1 Hemicellulose The structural carbohydrates are mixtures of polysaccharides which together with lignin, constitute the cell wall. Usually they are divided into three fractions: pectic substances, hemicellulose and cellulose.1 Pectins, widely ...
Hensanghongs, Patana
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Disaccharide Analysis of Glycosaminoglycans From Twenty‐Four Organs of Young and Aged Mice
Proteoglycan Research, Volume 3, Issue 1, January-March 2025.ABSTRACT Glycosaminoglycans (GAGs) are abundant negatively charged polysaccharides ubiquitously expressed in mammalian organs, having essential biological functions in development and homeostasis. It has been scarcely reported that GAG structures are changed in aged and diseased human organs; however, an overall landscape of GAGs in individual organs ...
Emil Tykesson +3 more
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RapA2 is a calcium-binding lectin composed of two highly conserved cadherin-like domains that specifically recognize Rhizobium leguminosarum acidic exopolysaccharides [PDF]
, 2012 In silico analyses have revealed a conserved protein domain (CHDL) widely present in bacteria that has significant structural similarity to eukaryotic cadherins. A CHDL domain was shown to be present in RapA, a protein that is involved in autoaggregation
Abdian, Patricia Lorena +3 more
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Nanoparticles and Glycosaminoglycans: Progress and Applications for Cancer Therapy
Proteoglycan Research, Volume 3, Issue 1, January-March 2025.ABSTRACT Glycosaminoglycans (GAGs) play essential roles in biological processes such as cell signaling and extracellular matrix assembly. Alterations in the structure of GAGs have been implicated in cancer pathogenesis, demonstrating their potential as biomarkers for cancer diagnosis and progression, as well as targets for pharmacological interventions.
Pietro Milesi +4 more
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The oxidation of ascorbic acid and its reduction in vitro and in vivo [PDF]
, 1937 The outstanding chemical property of ascorbic acid (vitamin C) is that it is a reducing agent. The suggestion is obvious that its physiological function may be associated with this property, and, if it is oxidized reversibly, with its behavior in an ...
Borsook, Henry +3 more
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