Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer [PDF]
Background Molecular markers identifying alterations in proliferation and apoptotic pathways could be particularly important in characterizing high-risk normal or pre-neoplastic tissue. We evaluated the following markers: Ki67, Minichromosome Maintenance
Yang Ximing J +4 more
doaj +4 more sources
TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions may share chromosomal changes with prostate cancer.
Nuno Cerveira +6 more
doaj +3 more sources
Background: Histopathological differentiation between BCH and HGPIN in prostatic needle biopsies is a diagnostic challenge. The gold standard for detection of HGPIN and BCH is histopathological examination; however subjectivity in interpretation and tiny
Fatma El-Zahraa Salah El-Deen Yassin +4 more
doaj +3 more sources
The Genitourinary Pathology Society and International Society of Urological Pathology Joint Expert Consultation Recommendations on intraductal carcinoma of the prostate. [PDF]
The GUPS–ISUP joint expert consultation on IDCP provides unified recommendations for the diagnosis, terminology, grading, and reporting of IDCP and atypical intraductal proliferation. Their adoption should reduce interobserver variation, facilitate consistent communication with clinicians, and improve patient management.
Shah RB +31 more
europepmc +2 more sources
Karsinomaprostat di Indonesia berada diurutan terbanyak kesepuluh dan urutan pertama terbanyak pada laki-laki. Adenokarsinomaprostat(AP) kadang sulit didiagnosis karena adanya gambaran morfologi menyerupai lesiganas, seperti high grade prostatic intra ...
Riefrini Nurlaili +3 more
doaj +1 more source
Current practices in prostate pathology reporting: results from a survey of genitourinary and general pathologists. [PDF]
This survey, conducted among a heterogeneous cohort of pathologists worldwide, describes the current reporting practice in prostate pathology. The main reporting practices in biopsies and radical prostatectomies were addressed, including reporting and quantifying pattern 4, methods of cancer volume quantification, case‐ versus specimen‐level grading ...
Nourbakshs M +51 more
europepmc +2 more sources
Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease-linked spectra-pathological signatures. [PDF]
Confocal Raman microspectroscopy for spatially resolved tissue analysis: technology setup, spectra‐pathological signatures derived from computational methods, and tissue‐level insights for biomedical research and clinical applications. Abstract Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of ...
Valous NA, Zörnig I, Jäger D.
europepmc +2 more sources
Why do we keep reporting high-grade prostatic intraepithelial neoplasia (HGPIN)? [PDF]
Katia R. M. Leite
doaj +2 more sources
Gleason Grade Group 4 prostate biopsy with no cancer seen on final pathology in the magnetic resonance imaging and Prostate Specific Membrane Antigen-Positron Emission Tomography era. [PDF]
Introduction The absence of prostate cancer on final surgical pathology after biopsy‐proven prostate cancer is a rare finding. Case presentation Case of pT0 prostate cancer following Gleason Grade Group 4 in 1 out of 12 cores from a transrectal ultrasound‐guided biopsy in a man who underwent both magnetic resonance imaging and 18F‐PSMA‐1007 Positron ...
Mookerji N +9 more
europepmc +2 more sources
Xanthogranulomatous Prostatitis Mimicking Prostate Carcinoma in A 78-Year-Old Male. [PDF]
ABSTRACT Prostate cancer is typically the leading diagnosis in patients with elevated PSA and abnormal digital rectal exam findings. Clinicians should consider mimickers such as xanthogranulomatous prostatitis in the differential diagnosis, particularly in cases with discordant PSA levels and imaging characteristics.
Salem MSEK +4 more
europepmc +2 more sources

