Results 11 to 20 of about 2,707 (196)

Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer [PDF]

open access: yesBMC Cancer, 2006
Background Molecular markers identifying alterations in proliferation and apoptotic pathways could be particularly important in characterizing high-risk normal or pre-neoplastic tissue. We evaluated the following markers: Ki67, Minichromosome Maintenance
Yang Ximing J   +4 more
doaj   +4 more sources

TMPRSS2-ERG Gene Fusion Causing ERG Overexpression Precedes Chromosome Copy Number Changes in Prostate Carcinomas, Paired HGPIN Lesions

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions may share chromosomal changes with prostate cancer.
Nuno Cerveira   +6 more
doaj   +3 more sources

Basal cell hyperplasia (BCH) versus high grade prostatic intraepithelial neoplasia (HGPIN) in tiny prostatic needle biopsies: Unusual diagnostic dilemma

open access: yesJournal of the Egyptian National Cancer Institute, 2014
Background: Histopathological differentiation between BCH and HGPIN in prostatic needle biopsies is a diagnostic challenge. The gold standard for detection of HGPIN and BCH is histopathological examination; however subjectivity in interpretation and tiny
Fatma El-Zahraa Salah El-Deen Yassin   +4 more
doaj   +3 more sources

The Genitourinary Pathology Society and International Society of Urological Pathology Joint Expert Consultation Recommendations on intraductal carcinoma of the prostate. [PDF]

open access: yesHistopathology
The GUPS–ISUP joint expert consultation on IDCP provides unified recommendations for the diagnosis, terminology, grading, and reporting of IDCP and atypical intraductal proliferation. Their adoption should reduce interobserver variation, facilitate consistent communication with clinicians, and improve patient management.
Shah RB   +31 more
europepmc   +2 more sources

Ekspresi alpha methylacyl co-a racemase (amacr) pada adenokarsinoma prostat dan high grade prostatic intraepithelial neoplasia (hgpin)

open access: yesJurnal Kedokteran dan Kesehatan, 2017
Karsinomaprostat di Indonesia berada diurutan terbanyak kesepuluh dan urutan pertama terbanyak pada laki-laki. Adenokarsinomaprostat(AP) kadang sulit didiagnosis karena adanya gambaran morfologi menyerupai lesiganas, seperti high grade prostatic intra ...
Riefrini Nurlaili   +3 more
doaj   +1 more source

Current practices in prostate pathology reporting: results from a survey of genitourinary and general pathologists. [PDF]

open access: yesHistopathology
This survey, conducted among a heterogeneous cohort of pathologists worldwide, describes the current reporting practice in prostate pathology. The main reporting practices in biopsies and radical prostatectomies were addressed, including reporting and quantifying pattern 4, methods of cancer volume quantification, case‐ versus specimen‐level grading ...
Nourbakshs M   +51 more
europepmc   +2 more sources

Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease-linked spectra-pathological signatures. [PDF]

open access: yesClin Transl Med
Confocal Raman microspectroscopy for spatially resolved tissue analysis: technology setup, spectra‐pathological signatures derived from computational methods, and tissue‐level insights for biomedical research and clinical applications. Abstract Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of ...
Valous NA, Zörnig I, Jäger D.
europepmc   +2 more sources

Why do we keep reporting high-grade prostatic intraepithelial neoplasia (HGPIN)? [PDF]

open access: yesInternational Brazilian Journal of Urology, 2016
Katia R. M. Leite
doaj   +2 more sources

Gleason Grade Group 4 prostate biopsy with no cancer seen on final pathology in the magnetic resonance imaging and Prostate Specific Membrane Antigen-Positron Emission Tomography era. [PDF]

open access: yesIJU Case Rep, 2023
Introduction The absence of prostate cancer on final surgical pathology after biopsy‐proven prostate cancer is a rare finding. Case presentation Case of pT0 prostate cancer following Gleason Grade Group 4 in 1 out of 12 cores from a transrectal ultrasound‐guided biopsy in a man who underwent both magnetic resonance imaging and 18F‐PSMA‐1007 Positron ...
Mookerji N   +9 more
europepmc   +2 more sources

Xanthogranulomatous Prostatitis Mimicking Prostate Carcinoma in A 78-Year-Old Male. [PDF]

open access: yesClin Case Rep
ABSTRACT Prostate cancer is typically the leading diagnosis in patients with elevated PSA and abnormal digital rectal exam findings. Clinicians should consider mimickers such as xanthogranulomatous prostatitis in the differential diagnosis, particularly in cases with discordant PSA levels and imaging characteristics.
Salem MSEK   +4 more
europepmc   +2 more sources

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