Chromosomal integration of HHV-6A during non-productive viral infection [PDF]
Scientific Reports, 2017 Human herpesvirus 6A (HHV-6A) and 6B (HHV-6B) are two different species of betaherpesviruses that integrate into sub-telomeric ends of human chromosomes, for which different prevalence rates of integration have been reported.
Nitish Gulve +3 more
doaj +7 more sources
HHV-6A Infection of Endometrial Epithelial Cells Induces Increased Endometrial NK Cell-Mediated Cytotoxicity [PDF]
Frontiers in Microbiology, 2017 Background: We have recently reported the presence of Human herpesvirus-6A (HHV-6A) DNA in the 43% of endometrial epithelial cells from primary idiopathic infertile women, with no positivity in fertile women.
Elisabetta Caselli +11 more
doaj +8 more sources
Presence of HHV-6A in Endometrial Epithelial Cells from Women with Primary Unexplained Infertility. [PDF]
PLoS ONE, 2016 To elucidate the roles of human herpesvirus (HHV)-6 primary unexplained infertile women, a prospective randomized study was conducted on a cohort of primary unexplained infertile women and a cohort of control women, with at least one successful pregnancy.
Roberto Marci +8 more
doaj +7 more sources
A complex evolutionary relationship between HHV-6A and HHV-6B.
Virus Evol, 2019 Human betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6, iciHHV6). We reconstructed the population structure of HHV-6 and we show that HHV-6A genomes
Forni D +4 more
europepmc +5 more sources
Paroxysmal Dyskinesias Secondary to HHV-6A Encephalitis: The First Case Report and Literature Review. [PDF]
Ann Clin Transl NeurolABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Wang Z +5 more
europepmc +4 more sources
Evolutionary analysis of exogenous and integrated HHV-6A/HHV-6B populations. [PDF]
Virus Evol, 2020 AbstractHuman betaherpesviruses 6A and 6B (HHV-6A and HHV-6B) are highly prevalent in human populations. The genomes of these viruses can be stably integrated at the telomeres of human chromosomes and be vertically transmitted (inherited chromosomally integrated HHV-6A/HHV-6B, iciHHV-6A/iciHHV-6B).
Forni D +4 more
europepmc +7 more sources
HHV-6A Infection of Endometrial Epithelial Cells Affects miRNA Expression and Trophoblast Cell Attachment. [PDF]
Reprod Sci, 2020 AbstractWe recently reported that human herpesvirus 6 (HHV-6) infection is frequently present in endometrial tissue of women with unexplained infertility, and that virus infection induces a profound remodulation of miRNA expression in human cells of different origin.
Bortolotti D +6 more
europepmc +5 more sources
gp96 Is Critical for both Human Herpesvirus 6A (HHV-6A) and HHV-6B Infections. [PDF]
J Virol, 2020 Although new clinical importance has been revealed for human herpesviruses 6A (HHV-6A) and 6B, much is still unknown about the life cycles of these viruses in target cells. We identified a novel cellular factor, gp96, that is critical for both HHV-6A and -6B entry into host cells.
Ma J +11 more
europepmc +6 more sources
Retraction to: A complex evolutionary relationship between HHV-6A and HHV-6B. [PDF]
Virus Evol, 2019 [This retracts the article DOI: 10.1093/ve/vez043.].
Forni D +4 more
europepmc +5 more sources
Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]
Frontiers in Microbiology, 2019 Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Anthony J. Saviola +12 more
doaj +3 more sources