Results 21 to 30 of about 2,937 (141)
Human herpesvirus 6B glycoprotein B postfusion structure, vulnerability mapping, and receptor recognition. [PDF]
PLoS PathogensHuman herpesvirus 6B (HHV-6B), a β-herpesvirus that significantly threatens immunocompromised individuals, currently lacks targeted antiviral therapies or vaccines. Glycoprotein B (gB), the primary mediator of membrane fusion during viral entry, is a key
Chu Xie +13 more
doaj +2 more sources
Hippocampal Atrophy in Pediatric Transplant Recipients with Human Herpesvirus 6B
Microorganisms, 2021 The aim of this study was to determine whether human herpesvirus 6B (HHV-6B) infection can impair the hippocampus in pediatric hematopoietic stem cell transplant (HSCT) recipients.
Misa Miyake +11 more
doaj +1 more source
Human Herpesvirus 6B U26 Inhibits the Activation of the RLR/MAVS Signaling Pathway
mBio, 2021 HHV-6B (human herpesvirus 6B) is well known to evade host antiviral responses and establish a lifelong latent infection. How HHV-6B evades RNA recognition is still poorly understood.
Xuefeng Jiang +14 more
doaj +1 more source
Viruses, 2021 Inherited chromosomally integrated (ici) human herpes virus 6 (HHV-6) is estimated to occur in 0.6–2.7% of people worldwide. HHV-6 comprises two distinct species: HHV-6A and HHV-6B. Both HHV-6A and HHV-6B integration have been reported. Several drugs are
Laure Izquierdo +6 more
doaj +1 more source
Human herpesvirus 6B infection in mesial temporal lobe epilepsy: a meta-analysis
Acta Epileptologica, 2022 Background Whether human herpesvirus 6B (HHV-6B) can affect mesial temporal lobe epilepsy (MTLE) remains controversial. The present meta-analysis was aimed to evaluate whether HHV-6B is significantly associated with MTLE.
Jingyi Tong +8 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Quantitative HHV-6B antigenemia test for the monitoring of transplant patients [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2010 Human herpesvirus-6 (HHV-6) infection, mostly caused by variant B, is common after transplantation. Here, we report a new modified method using an HHV-6B glycoprotein IgG antibody, OHV-3, and attempt to quantify the HHV-6 antigenemia after liver transplantation.
Loginov, R. +4 more
openaire +4 more sources
eLife, 2021 Human herpesviruses 6A and 6B (HHV-6A/6B) are ubiquitous pathogens that persist lifelong in latent form and can cause severe conditions upon reactivation.
Michael L Wood +14 more
doaj +1 more source
Nectin-2 Acts as a Viral Entry Mediated Molecule That Binds to Human Herpesvirus 6B Glycoprotein B
Viruses, 2022 Human herpesvirus 6B (HHV-6B) is a T-lymphotropic virus and the etiological agent of exanthem subitum. HHV-6B is present in a latent or persistent form after primary infection and is produced in the salivary glands or transmitted to this organ.
Hirohito Ogawa +5 more
doaj +1 more source
Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6
BMC Genomics, 2018 Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger +19 more
doaj +1 more source