Results 161 to 170 of about 78,371,982 (236)

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

open access: yesAdvanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha   +5 more
wiley   +1 more source

Assembly-graph-assisted haplotype-resolved scaffolding of polyploid genomes. [PDF]

open access: yesNat Plants
Du W   +13 more
europepmc   +1 more source

Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems

open access: yesAdvanced Science, EarlyView.
This study quantifies photosynthesized C allocation in the plant–soil system across six crop types: barley, wheat, maize, rice, legumes and grasses. It reports C partitioning into shoot respiration, shoot‐C, root‐C, net rhizodeposition and root‐derived CO2, providing standardized percentage averages and GPP‐derived absolute values as a robust baseline ...
Zhengjun Yan   +10 more
wiley   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li   +15 more
wiley   +1 more source

Resolving Host-Associated Antimicrobial Resistance in Municipal Wastewater Using Hi-C Metagenomics. [PDF]

open access: yesMicroorganisms
Senok A   +8 more
europepmc   +1 more source

Freestanding PZT Films for Integrated Wearable Sensing and Intelligent Acoustic Recognition

open access: yesAdvanced Science, EarlyView.
A freestanding epitaxial PZT/LaNiO3/Pt heterostructure is achieved via water‐assisted delamination from mica, effectively eliminating substrate‐induced clamping and releasing intrinsic ferroelectricity. The released film exhibits substantially enhanced remanent polarization and piezoelectric response, delivering excellent mechanical flexibility and ...
Hailong Pan   +6 more
wiley   +1 more source

Hardware Acceleration of Stochastic Neural Networks Enabled by Bit‐Cell Level Co‐Design of Magnetic Tunnel Junctions

open access: yesAdvanced Science, EarlyView.
An MTJ‐based probabilistic processing‐in‐memory architecture unites nonvolatile storage, local entropy generation, and stochastic computation within each memory cell. Stored multi‐bit weights are converted directly into programmable stochastic bitstreams, enabling neural‐network inference, adaptive Ising optimization, and uncertainty‐aware Bayesian ...
Qiuyuan Wang   +6 more
wiley   +1 more source

Balancing Shading and Resistive Losses: 33% Efficient Perovskite/Silicon Tandem Solar Cells via Front‐Electrode Engineering

open access: yesAdvanced Science, EarlyView.
Front‐electrode co‐optimization combining tungsten‐doped indium oxide (IWO) transparent electrode and simulation‐guided metal grid geometry boosts perovskite/silicon tandem solar cell performance. The low work function IWO improves interfacial carrier extraction, while tailored grid parameters balance optical shading and electrical resistive losses ...
Yuhui Ji   +15 more
wiley   +1 more source

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