Results 241 to 250 of about 260,200 (252)

Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-232 in Complex with the Reactivator, HI-6

, 2020
S. Bester, M. Guelta, J. Height, S. Pegan   +3 more
semanticscholar   +1 more source

Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics.

Toxicology, 2016
F. Worek, M. Koller, H. Thiermann, T. Wille   +3 more
semanticscholar   +1 more source

Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6

Archives of Toxicology, 2016
T. Wille, Jens von der Wellen, H. Thiermann, F. Worek   +3 more
semanticscholar   +1 more source

Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with VX(+) and HI-6

, 2018
S. Bester, M. Guelta, S. Pegan, J. Height   +3 more
semanticscholar   +2 more sources

A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice

Toxicology Mechanisms and Methods, 2015
J. Kassa, V. Sepsova, L. Matoušková, A. Horova, K. Musílek   +4 more
semanticscholar   +1 more source

Freeze-drying of HI-6-loaded recombinant human serum albumin nanoparticles for improved storage stability.

European journal of pharmaceutics and biopharmaceutics, 2014
M. Dadparvar, Sylvia Wagner, Sascha L. Wien, F. Worek, H. von Briesen, J. Kreuter   +5 more
semanticscholar   +1 more source

Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with EMPA and HI-6

, 2018
S. Bester, M. Guelta, S. Pegan, J. Height   +3 more
semanticscholar   +1 more source

Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes

Emergency Medicine Journal, 2014
S. Hill, Simon H L Thomas, P. Flecknell, Aurelie Thomas, C. Morris, D. Henderson, M. Dunn, P. Blain   +7 more
semanticscholar   +1 more source

In vitro and in vivo genotoxicity assessment of HI-6 dimethanesulfonate/oxime.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2014
L. Nakab, I. Bardot, S. Bardot, S. Simar, D. Marzin, F. Nesslany   +5 more
semanticscholar   +1 more source

Structure of a pre-reaction ternary complex between sarin- acetylcholinesterase and HI-6

, 2016
A. Allgardsson, L. Berg, C. Akfur, A. Hornberg, F. Worek, A. Linusson, F. Ekström   +6 more
semanticscholar   +1 more source