Türk Patoloji Dergisi, 2018 Objective: Deviations in the apoptotic process have been demonstrated in prostate carcinogenesis. We aimed to evaluate especially the process of extrinsic apoptosis in the spectrum of neoplastic lesions of the prostate epithelium so as to reveal the ...
Ayşe Burcu İLERİ +5 more
doaj +1 more source
Predicting prostate biopsy outcome: Prostate health index (phi) and prostate cancer antigen 3 (PCA3) are useful biomarkers [PDF]
, 2012 Indication for prostate biopsy is presently mainly based on prostate-specific antigen (PSA) serum levels and digital-rectal examination (DRE). In view of the unsatisfactory accuracy of these two diagnostic exams, research has focused on novel markers to ...
A. D. Carlo +13 more
core +1 more source
The use of immunohistochemistry for diagnosis of prostate cancer [PDF]
, 2010 PURPOSE: Atypical glands (ASAP) are diagnosed in 5.0% of prostate biopsies, and cancer identification in a rebiopsy is higher than 40.0%. The use of antibodies to mark basal cells is currently a common practice, in order to avoid rebiopsies.
ANTUNES, Alberto A. +7 more
core +2 more sources
Prostate biopsies containing prostate intraepithelial neoplasia and atypical small acinar proliferation: what to do? [PDF]
Einstein (São Paulo), 2009 Objective: The aim of the study was to assess the frequency of high-grade prostate intraepithelial neoplasia and atypical small acinar proliferations on a contemporary series, and their relation to posterior diagnosis of prostate cancer.
Fernando Korkes +3 more
doaj
Heat shock protein 90 is associated with hyperplasia and neoplastic transformation of canine prostatic epithelial cells [PDF]
, 2014 Heat shock protein 90 (HSP90) is a molecular chaperone that regulates critical signalling proteins of cancer development and progression. Abnormal levels of HSP90 have been observed in human prostatic carcinoma (PC), with prognostic and therapeutic ...
Benazzi, C. +3 more
core +1 more source
European Journal of Histochemistry, 2009 The antigen Ki-67, which is associated with cell proliferation, has been demonstrated to be useful in predicting the development of human tumors. The objective of this study was to evaluate the prognostic utility of this biomarker in pre-malignant and ...
E Muñoz, F Gómez, JI Paz, I Casado
doaj +1 more source
KI-67 IMMUNOHISTOHEMICAL EXPRESSION IN PROSTATIC LESIONS
The Iraqi Journal of Medical Sciences, 2017 Background: The cell proliferation marker, ki-67, is a nuclear and nucleolar protein, which can be detected during all active phases of the cell cycle (G1, S, G2, and mitosis), but absent from cell resting phases.
Inas A. Rasheed +2 more
doaj +6 more sources
Diagnostic utility of α-methylacyl CoA racemase (P504S) & HMWCK in morphologically difficult prostate cancer [PDF]
, 2010 Background To evaluate the diagnostic utility of alpha-methylacyl CoA racemase (P504S) & HMWCK (34beta E12) in morphologically difficult prostate cancer.
K Kumaresan +5 more
core +1 more source
Basal cell markers:34BE12 and p63, improving detection of basal cells in atypical prostatic lesions
مجله كليه طب الكندي, 2019 Background: The diagnosis of prostatic pathology may be of challenging , as some difficult and suspected, atypical cases may lack basal cell layer by routine H&E sections . Antibodies against 34BE12(HMW-CK) and p63 aid the diagnosis of such cases ,
Inas A. Rasheed
doaj +1 more source
A trial of risk‐adapted prostate cancer screening in a federally supported health center network serving a high‐risk population [PDF]
CancerAbstract Background Although Black men experience earlier onset and higher mortality from prostate cancer (PCa), no studies to date have tested interventions that encourage adoption of risk‐adapted prostate‐specific antigen (PSA) screening. The authors conducted a 15‐month trial in clinics serving Chicago communities with high PCa mortality and Black ...
Gann P +10 more
europepmc +2 more sources