Results 121 to 130 of about 18,911,331 (239)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Escherichia coli high-risk clone ST410 harboring bla_NDM-13 isolated from hospital wastewater in China. [PDF]

Environ Sci Pollut Res Int, 2023
Ju X, Wu Y, Chen G, Zhang R.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Management of high-risk acute pulmonary embolism : an emulated target trial analysis

: BackgroundHigh-risk acute pulmonary embolism (PE) is a life-threatening condition necessitating hemodynamic stabilization and rapid restoration of pulmonary perfusion.
Schwinger, Robert H.G., Kriz, Marvin, Spieth, Peter M., Kilo, Juliane, Haeberle, Helene, Schaefer, Andreas, Tautz, Esther, Zeymer, Uwe, Vrints, Christiaan, Villegas Sierra, Laura, Hoepler, Julia, Crusius, Lisa, Luesebrink, Enzo, Thiele, Holger, Schomaker, Michael, Billig, Hannah, Tavazzi, Guido, Uribarri, Aitor, Nickenig, Georg, Frank, Derk, Scherer, Clemens, Verstraete, Andreas, Salem, Mostafa, Hullermann, Carsten, Pappalardo, Federico, Moises, Jorge, De Roeck, Frederic, Tongers, Joern, Riera, Jordi, Rangel, Rafael Henrique, Goslar, Tomaz, Jung, Christian, Knorr, Maike, Tichelbaecker, Tobias, Hoffmann, Sabine, Adler, Christoph, Schrage, Benedikt, Stadlbauer, Andrea, Borst, Oliver, Binzenhoefer, Leonhard, Kraft, Marie, Erglis, Andrejs, Skurk, Carsten, Zilberszac, Robert, Westermann, Dirk, Terauda, Elizabete, Combes, Alain, Sabate, Manel, Camboni, Daniele, Kufner, Sebastian, Verbelen, Tom, Moebius-Winkler, Sven, Massberg, Steffen, Schmid, Christof, Zimmer, Sebastian, Hagl, Christian, Supady, Alexander, El-Essawi, Aschraf, Mangner, Norman, Hoyer, Daniel, Graf, Tobias, Speidl, Walter S., Haertel, Franz, Chiscano-Camon, Luis, Roncon-Albuquerque Jr, Roberto, Noc, Marko, Majunke, Nicolas   +66 more
core  

Endemicity of Pseudomonas aeruginosa producing IMP-18 and/or VIM-2 MBLs from the high-risk clone ST111 in Central America. [PDF]

JAC Antimicrob Resist, 2023
Deshpande LM, Vega S, Tinoco JC, Castanheira M.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Whole-Genome Sequencing of 11 High-Risk Clone ST111 Pseudomonas aeruginosa Isolates from French Hospitals. [PDF]

Microbiol Resour Announc, 2023
Anbo M, Chichkova MAT, Gençay YE, Salazar A, Jeannot K, Jelsbak L.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Investigation of Delafloxacin Resistance in Multidrug-Resistant Escherichia coli Strains and the Detection of E. coli ST43 International High-Risk Clone. [PDF]

Microorganisms, 2023
Gulyás D, Kamotsay K, Szabó D, Kocsis B.   +3 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source