Results 181 to 190 of about 267,333 (289)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Clonal dissemination of carbapenem-resistant Klebsiella pneumoniae in outpatients as fecal-carriages: predominance of the high-risk clone ST231. [PDF]

BMC Infect Dis
Soltani Shirazi A, Kiani N, Aghamohammad S, Shafiei M, Alavi Darazam I, Darabi S, Badmasti F.   +6 more
europepmc   +1 more source

Whole Genome Characterization of the High-Risk Clone ST383 Klebsiella pneumoniae with a Simultaneous Carriage of bla_CTX-M-14 on IncL/M Plasmid and bla_CTX-M-15 on Convergent IncHI1B/IncFIB Plasmid from Egypt. [PDF]

Microorganisms, 2022
Edward EA, Mohamed NM, Zakaria AS.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Emergence of <i>tmexCD1-toprJ1</i> in the clinical high-risk clone sequence type 147 among carbapenem-resistant <i>Klebsiella pneumoniae</i> isolates in China: A multicentre retrospective study. [PDF]

Virulence
Wang C, Shen S, Gao X, Huang X, Wang Y, Lv L, Yue C, Yu H, Sun Z, Liu JH, Hu F.   +10 more
europepmc   +1 more source

Genomic Characterization of International High-Risk Clone ST410 Escherichia coli Co-Harboring ESBL-Encoding Genes and bla_NDM-5 on IncFIA/IncFIB/IncFII/IncQ1 Multireplicon Plasmid and Carrying a Chromosome-Borne bla_CMY-2 from Egypt. [PDF]

Antibiotics (Basel), 2022
Mohamed NM, Zakaria AS, Edward EA.
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

ICU environment as a reservoir of KPC-ST307-Klebsiella pneumoniae high-risk clone resistant to ceftazidime-avibactam. [PDF]

Sci Rep
Hernández-García M, Nieto-Torres M, Guerra-Pinto N, Castillo-Polo JA, Saez de la Fuente J, Michelena M, Ponce-Alonso M, Soriano-Cuesta C, Díaz-Agero C, Cantón R, Coque TM, Ruiz-Garbajosa P.   +11 more
europepmc   +1 more source

Antimicrobial Resistance and Type III Secretion System Virulotypes of Pseudomonas aeruginosa Isolates from Dogs and Cats in Primary Veterinary Hospitals in Japan: Identification of the International High-Risk Clone Sequence Type 235. [PDF]

Microbiol Spectr, 2021
Hayashi W, Izumi K, Yoshida S, Takizawa S, Sakaguchi K, Iyori K, Minoshima KI, Takano S, Kitagawa M, Nagano Y, Nagano N.   +10 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source