Results 191 to 200 of about 267,333 (289)

Escherichia coli high-risk clone - Influence of the elder population in dissemination

European Journal of Public Health, 2019
D Gonçalves, P Cecílio, H Ferreira
openaire   +3 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Outbreak of Carbapenem-Resistant High-Risk Clone ST244 of <i>Pseudomonas aeruginosa</i> in Dogs and Cats in Algeria. [PDF]

Antibiotics (Basel)
Badis A, Heleili N, Merradi M, Ayachi A, Martino PA, Meroni G, Soggiu A.   +6 more
europepmc   +1 more source

Species Transferability of Klebsiella pneumoniae Carbapenemase-2 Isolated from a High-Risk Clone of Escherichia coli ST410. [PDF]

J Microbiol Biotechnol, 2020
Lee M, Choi TJ.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Preventing Emergence of Antibiotic Resistant High-Risk Clones of Pseudomonas aeruginosa

, 2023
Pseudomonas aeruginosa is a devastating hospital pathogen, which plays a prominent role in the ongoing antimicrobial resistance crisis. To understand this pathogen, it is necessary to closely examine the genetic factors (virulence factors) that enable this bacteria to cause infection and disease.
openaire   +1 more source

Analysis of intrahospital and global dissemination and resistome dynamics of NDM-1-producing ST773 <i>Pseudomonas aeruginosa</i> high-risk clone. [PDF]

JAC Antimicrob Resist
Pitart C, Taltavull G, López-Causapé C, Pulgarín A, De Gea S, Aguilar M, Mulet X, Cabot G, Vila J, Roca I, Espasa M, Casals-Pascual C, Oliver A.   +12 more
europepmc   +1 more source

Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae ST-15. [PDF]

Proc Natl Acad Sci U S A, 2020
Gato E, Vázquez-Ucha JC, Rumbo-Feal S, Álvarez-Fraga L, Vallejo JA, Martínez-Guitián M, Beceiro A, Ramos Vivas J, Sola Campoy PJ, Pérez-Vázquez M, Oteo Iglesias J, Rodiño-Janeiro BK, Romero A, Poza M, Bou G, Pérez A.   +15 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source