Results 51 to 60 of about 267,333 (289)

Genome dynamics of high-risk resistant and hypervirulent Klebsiella pneumoniae clones in Dhaka, Bangladesh

Frontiers in Microbiology, 2023
Klebsiella pneumoniae is recognized as an urgent public health threat because of the emergence of difficult-to-treat (DTR) strains and hypervirulent clones, resulting in infections with high morbidity and mortality rates. Despite its prominence, little is known about the genomic epidemiology of K. pneumoniae in resource-limited settings like Bangladesh.
Arif Hussain, Razib Mazumder, Amira Ahmed, Umme Saima, Jody Phelan, Susana Campino, Dilruba Ahmed, Md Asadulghani, Taane G. Clark, Dinesh Mondal   +9 more
openaire   +3 more sources

A common founding clone with TP53 and PTEN mutations gives rise to a concurrent germ cell tumor and acute megakaryoblastic leukemia [PDF]

, 2016
We report the findings from a patient who presented with a concurrent mediastinal germ cell tumor (GCT) and acute myeloid leukemia (AML). Bone marrow pathology was consistent with a diagnosis of acute megakaryoblastic leukemia (AML M7), and biopsy of an ...
Demeter, Ryan T, Duncavage, Eric J, Griffith, Malachi, Griffith, Obi L, Hagemann, Ian S, Lu, Charles, Magrini, Vincent, Miller, Christopher A, O\u27Laughlin, Michelle, Ozenberger, Bradley A, Riedell, Peter, Wartman, Lukas D, Westervelt, Peter   +12 more
core   +2 more sources

Nosocomial dissemination of hypervirulent Klebsiella pneumoniae with high-risk clones among children in Shanghai

Frontiers in Cellular and Infection Microbiology, 2022
ObjectivesAlthough hypervirulent Klebsiella pneumoniae (hvKp) is an increasing public health problem, there remains limited epidemiological information regarding hvKp infections in children. Here, we conducted a clinical, molecular and phenotypic surveillance of hvKp strains in a pediatric population.MethodsNon-repetitive K.
Qingqing Du, Fen Pan, Chun Wang, Fangyuan Yu, Yingying Shi, Wenxin Liu, Zhi Li, Ping He, Dingding Han, Hong Zhang   +9 more
openaire   +3 more sources

A Split-Stem Lesion on Young Hybrid \u3ci\u3ePopulus\u3c/i\u3e Trees Caused by the Tarnished Plant Bug, \u3ci\u3eLygus Lineolaris\u3c/i\u3e (Hemiptera: [Heteroptera]: Miridae) [PDF]

, 2017
The tarnished plant bug, known principally as an agricultural pest, injures young hybrid Populus by feeding on the stems and meristems. Tarnished plant bug eggs, fungi associated with some lesions, and simple mechanical stimuli alone from feeding ...
Ostry, Michael E, Sapio, Frank J, Wilson, Louis F   +2 more
core   +2 more sources

The type III secretion system facilitates systemic infections of Pseudomonas aeruginosa in the clinic

Microbiology Spectrum
Pseudomonas aeruginosa is a major opportunistic pathogen that can cause severe systemic infections. Here, we found that the type III secretion system effector ExoU was the main determinant of pathogenicity of a highly virulent clinical isolate strain ...
Tiantian Wu, Zhenchuan Zhang, Tong Li, Xu Dong, Dan Wu, Lixia Zhu, Kaijin Xu, Ying Zhang   +7 more
doaj   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

High-risk Escherichia coli clones that cause neonatal meningitis and association with recrudescent infection

eLife, 2023
Abstract Neonatal meningitis is a devastating disease associated with high mortality and neurological sequelae. Escherichia coli is the second most common cause of neonatal meningitis in full-term infants (herein NMEC) and the most common cause of meningitis in preterm neonates ...
Nguyen Thi Khanh Nhu, Minh-Duy Phan, Steven J. Hancock, Kate M. Peters, Laura Alvarez-Fraga, Brian M. Forde, Stacey B. Andersen, Thyl Miliya, Patrick N.A. Harris, Scott A. Beatson, Sanmarie Schlebusch, Haakon Bergh, Paul Turner, Annelie Brauner, Benita Westerlund-Wikström, Adam D. Irwin, Mark A. Schembri   +16 more
openaire   +7 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Genomic features of a carbapenem-resistant OXA-219-positive Acinetobacter baumannii of international ST15 (CC15) from a patient with community-onset urinary tract infection in Chilean Patagonia

Journal of Global Antimicrobial Resistance, 2020
Objective: Carbapenemase-producing Acinetobacter baumannii has been recognized as a critical priority pathogen by the World Health Organization. We hereby report the identification and the draft genome sequence of a carbapenem-resistant A.
Sebastián Cifuentes, Quézia Moura, Brenda Cardoso, Fernanda Esposito, Louise Cerdeira, Estefanía Álvarez, Edgard Barrera, Andrés Opazo-Capurro, Gerardo Gonzalez-Rocha, Nilton Lincopan   +9 more
doaj   +1 more source

Heterologous screening of hybridomas for the development of broad-specific monoclonal antibodies against deoxynivalenol and its analogues [PDF]

, 2014
Hapten heterology was introduced into the steps of hybridoma selection for the development of monoclonal antibodies (MAbs) against deoxynivalenol (DON).
Bracke, Marc, De Saeger, Sarah, Deforce, Dieter, Eremin, S, Galvita, Anastasia, Guo, Yirong, Heyerick, Arne, Sanders, Melanie   +7 more
core   +1 more source