Results 41 to 50 of about 267,333 (289)
Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance. [PDF]
, 2017 With the continued emergence of risk loci from Genome-Wide Association studies and variants of uncertain significance identified from patient sequencing, better methods are required to translate these human genetic findings into improvements in public ...
Carvajal-Carmona, Luis G +4 more
core +4 more sources
Microorganisms, 2023 Acinetobacter baumannii is a Gram-negative coccobacillus with exceptional survival skills in an unfavorable environment and the ability to rapidly acquire antibiotic resistance, making it one of the most successful hospital pathogens worldwide, representing a serious threat to public health. The global dissemination of A. baumannii is driven by several
Andrey Shelenkov +2 more
openaire +3 more sources
mSystems, 2020 Genotyping of 2,882 Pseudomonas aeruginosa isolates that had been collected during the last 40 years identified the ExoU-positive lineages PA14 (ST253) and ST235 as the second and third most frequent clones in the P. aeruginosa population.
Sebastian Fischer +3 more
doaj +1 more source
Transmissible silver resistance readily evolves in high-risk clone isolates of Klebsiella pneumoniae [PDF]
Acta Microbiologica et Immunologica Hungarica, 2018 Silver is used extensively in both hospitals and outpatient clinics as a disinfectant coating agent on various devices. Resistance to silver was recently reported as an emerging problem inEnterobacteriaceae.Multidrug-resistant high-risk clones ofKlebsiella pneumoniaeare common causes of serious healthcare-associated infections worldwide posing a ...
Hanczvikkel, Adrienn +3 more
openaire +3 more sources
Microorganisms, 2019 Virulence plasmids are associated with hypervirulent types of Klebsiella pneumoniae, which generally do not carry antibiotic resistance genes. In contrast, nosocomial isolates are often associated with resistance, but rarely with virulence plasmids. Here,
Jane Turton +5 more
doaj +1 more source
Characterization of an emergent clone of enteroinvasive Escherichia coli circulating in Europe [PDF]
, 2016 Enteroinvasive Escherichia coli (EIEC) cause intestinal illness indistinguishable from that caused by Shigella, mainly in developing countries. Recently an upsurge of cases of EIEC infections has been observed in Europe, with two large outbreaks ...
Caprioli, A. +9 more
core +1 more source
Co-existence of OXA-48 and NDM-1 in colistin resistant Pseudomonas aeruginosa ST235
Emerging Microbes and Infections, 2020 Here, we presented 11 cases with colistin-resistant Pseudomonas aeruginosa infection and co-existence of OXA-48 and NDM-1 in the ST235 high-risk clone. The molecular analyses were performed by Sanger sequencing and RT–PCR.
Cansel Vatansever +6 more
doaj +1 more source
Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice [PDF]
, 2019 We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals.
Carestia, Agostina +9 more
core +1 more source
Open Forum Infectious Diseases, 2023 Abstract Background Pseudomonas aeruginosa (PAE) is an opportunistic pathogen associated with a variety of hospital infections. Treatment of infections caused by PAE is challenging due to the emergence of multidrug-resistant (MDR), which is associated with increased morbidity, mortality, and ...
Zurita, Jeannete +4 more
openaire +1 more source
Insulin-like growth factor-1 is a negative modulator of glucagon secretion [PDF]
, 2017 Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose.
Andreozzi, F +6 more
core +1 more source