Results 1 to 10 of about 1,952 (169)

Genomic characterization of carbapenemase-producing Klebsiella pneumoniae ST307 revealed multiple introductions in Buenos Aires, Argentina [PDF]

Journal of Global Antimicrobial Resistance
: Objectives: To describe at genomic level nine carbapenemase-producing Klebsiella pneumoniae ST307 (Kp-ST307) clinical isolates recovered in Buenos Aires during 2017 to 2021, investigating their resistome, virulome, and phylogeny.
Francisco Gonzalez Espinosa, José Alejandro Di Conza, Gian Maria Rossolini   +2 more
exaly   +12 more sources

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High‐Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa [PDF]

MicrobiologyOpen
Asymptomatic rectal carriers are recognized as reservoirs of carbapenem‐resistant Klebsiella pneumoniae (CRKp), which can spread epidemic high‐risk clones [e.g., sequence types (ST)‐307] and plasmids [incompatibility group (Inc)‐X3] in hospitals, with ...
Kafilat Taiwo Salvador‐Oke, Johann Pitout, Gisele Peirano, Kathy‐Anne Strydom, Chanel Kingsburgh, Marthie Ehlers, Marleen Kock   +6 more
doaj   +3 more sources

Emerging high-risk ST101 and ST307 carbapenem-resistant Klebsiella pneumoniae clones from bloodstream infections in Southern Italy [PDF]

Annals of Clinical Microbiology and Antimicrobials, 2020
Background Carbapenem-resistant Klebsiella pneumoniae (CR-KP) is an urgent public health issue in Italy. This pattern of resistance is due mainly to dissemination of carbapenemase genes.
Daniela Loconsole, Marisa Accogli, Loredana Capozzi   +2 more
exaly   +8 more sources

Report of High-Risk Carbapenem-Resistant K. pneumoniae ST307 Clone Producing KPC-2, SHV-106, CTX-M-15, and VEB-1 in Greece [PDF]

Antibiotics
Background/Objectives: Klebsiella pneumoniae ST307 is emerging as a significant global high-risk antimicrobial-resistant (AMR) clone with a notable capacity to acquire and disseminate resistance genes.
Maria Chatzidimitriou, Pandora Tsolakidou, Maria Anna Kyriazidi, Sotiris Varlamis, Ilias S. Frydas, Maria Mavridou, Stella Mitka   +6 more
doaj   +3 more sources

Emergence and regional spread of extended-spectrum β-lactamase-producing Klebsiella pneumoniae ST307 at a Japanese tertiary-care hospital [PDF]

Microbiology Spectrum
The global emergence of extended-spectrum β-lactamase-producing Klebsiella pneumoniae (ESBL-Kp), especially antimicrobial-resistant high-risk clones, is a public health concern. However, data on their molecular epidemiology in Japan remain limited.
Wataru Ito, Ryuichi Nakano, Akiyo Nakano, Yuki Suzuki, Hisakazu Yano, Kei Kasahara   +5 more
doaj   +2 more sources

Genomic analysis of carbapenem-resistant Klebsiella pneumoniae blood isolates from nationwide surveillance in South Korea [PDF]

Frontiers in Microbiology
IntroductionCarbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to public health owing to its multidrug resistance and rapid dissemination.MethodsThis study analyzed CRKP isolates collected from bloodstream infections in nine ...
Younggwon On, Jung Wook Kim, Juyoung Lee, Jung Sik Yoo   +3 more
doaj   +2 more sources

Convergence of multidrug resistance and efflux-mediated biocide tolerance in klebsiella pneumoniae ST307: implications for nosocomial infection control in Iranian hospitals [PDF]

BMC Infectious Diseases
Background The relentless evolution of K. pneumoniae ST307 into a “superbug” with dual resistance to last-line antibiotics and hospital disinfectants poses an existential threat to infection control.
Rezvan Goodarzi, Sima Kazemi, Mohammad Hossein Nasershariati, Babak Asghari   +3 more
doaj   +2 more sources

Iron metabolism contributes to virulence by enhancing serum resistance in the emerging high-risk clone ST15 CRKP [PDF]

Virulence
ST15 has become one of the most common sequence types of carbapenem-resistant Klebsiella pneumoniae (CRKP) in China; however, the characteristics of ST15 CRKP remains elusive. This study included a total of 72 unique CRKP isolates, comprising ST15, ST11,
Jingjing Chen, Hailong Li, Fushun Li, Mingming Kang, Ruixuan Wang, Yunzhuo Chu, Xiaoxu Han, Hong Shang   +7 more
doaj   +2 more sources

Meropenem/vaborbactam activity against carbapenem-resistant Klebsiella pneumoniae from catheter-related bloodstream infections [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionCarbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat in oncology settings due to its multidrug resistance and ability to form biofilms on indwelling medical devices.MethodsThis study investigated the in vitro and in ...
Francesca Sivori, Massimo Francalancia, Mauro Truglio, Ilaria Cavallo, Carmelina Pronesti, Giorgia Fabrizio, Ilaria Celesti, Andrea Cazzani, Lorenzo Furzi, Fulvia Pimpinelli, Enea Gino Di Domenico   +10 more
doaj   +2 more sources

Transmission dynamics of Klebsiella pneumoniae in a neonatal intensive care unit in Zambia before and after an infection control bundle. [PDF]

PLOS Global Public Health
Klebsiella pneumoniae is a leading cause of neonatal sepsis in low- and middle-income countries, with antimicrobial resistance (AMR) significantly contributing to mortality. We used whole genome sequencing to explore the impact of an infection prevention
Laura T Phillips, Matthew Bates, Susan E Coffin, Ebenezer Foster-Nyarko, Monica Kapasa, Sylvia Machona, Lawrence Mwananyanda, James C L Mwansa, Chileshe L Musyani, John M Tembo, Franklyn N Egbe, Kathryn E Holt, Davidson H Hamer   +12 more
doaj   +2 more sources