Results 31 to 40 of about 1,531 (135)

ICU environment as a reservoir of KPC-ST307-Klebsiella pneumoniae high-risk clone resistant to ceftazidime-avibactam [PDF]

Scientific Reports
We characterized all ceftazidime-avibactam-resistant KPC-producing K. pneumoniae (KPC-Kp) isolates recovered from both patients and environmental samples at the ICU of our hospital in 2020, during the COVID-19 pandemic initiation.
Marta Hernández-García, Marta Nieto-Torres, Natalia Guerra-Pinto, Juan Antonio Castillo-Polo, Javier Saez de la Fuente, Malkoa Michelena, Manuel Ponce-Alonso, Cruz Soriano-Cuesta, Cristina Díaz-Agero, Rafael Cantón, Teresa M. Coque, Patricia Ruiz-Garbajosa   +11 more
doaj   +2 more sources

Genomic and Functional Characterization of CTX-M-15-Producing Klebsiella pneumoniae ST307 Isolated from Imported Leopard Tortoises in Germany

Applied Microbiology
The Klebsiella pneumoniae ST307 clone, identified in the mid-1990s, has emerged as a global antimicrobial-resistant (AMR) high-risk clone, significantly contributing to the global health challenge also posed by other AMR K. pneumoniae lineages.
Tammy J. Schmidt, Sophie Aurich, Franziska Unger, Tobias Eisenberg, Christa Ewers   +4 more
doaj   +2 more sources

Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020 [PDF]

Antimicrobial Resistance and Infection Control
Background The emergence and spread of third-generation cephalosporins (3GC) and carbapenem-resistant Klebsiella pneumoniae pose a global critical challenge.
Neris García-González, Beatriz Beamud, Jordi Sevilla-Fortuny, Victoria Sánchez-Hellín, Inmaculada Vidal, Juan Carlos Rodríguez, Begoña Fuster, Nuria Tormo, Carme Salvador, Concepción Gimeno, Barbara Gomila-Sard, Salvador Giner, Olalla Martínez, Javier Colomina, David Navarro, Victoria Domínguez, on behalf of Networked Laboratory for the Surveillance of Antimicrobial Resistance of the Valencian Community, Fernando González-Candelas   +17 more
doaj   +2 more sources

Emergence and clonal expansion of Klebsiella pneumoniae ST307, simultaneously producing KPC-3 and NDM-1 [PDF]

, 2022
Klebsiella pneumoniae ST307 es un clon de alto riesgo, cuyas características genéticas contribuyen a su adaptación al entorno hospitalario y al huésped humano. Este estudio describe la emergencia y diseminación clonal de aislamientos de K.
Cejas, Daniela, Elena, Alan Xavier, Yernazian, María Valeria, Ormazábal, Cecilia, Magariños, Francisco, Ferrara, Micaela Magalí, Gutkind, Gabriel Osvaldo, Radice, Marcela Alejandra   +7 more
core   +1 more source

Carbapenemase-producing Klebsiella pneumoniae strains in Switzerland: human and non-human settings may share high-risk clones

Journal of Global Antimicrobial Resistance, 2022
: Background: The spread of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) strains belonging to high-risk sequence types (STs) is a concern. For Switzerland, national data about the molecular features (especially the STs) of CP-Kp of human origin
Edgar I. Campos-Madueno, Aline I. Moser, Géraldine Jost, Carola Maffioli, Thomas Bodmer, Vincent Perreten, Andrea Endimiani   +6 more
doaj   +1 more source

Epidemiological Study of KPC-2 Producing Klebsiella pneumoniae Isolated in Daejeon During a 4-Year Period

Korean Journal of Clinical Laboratory Science, 2022
The emergence and dissemination of carbapenemase-producing Enterobacteriaceae (CPE), particularly the Klebsiella pneumoniae carbapenemase-2 (KPC-2) producing Klebsiella pneumoniae, has been rapidly increasing worldwide and is becoming a serious public ...
Hye Hyun Cho
doaj   +1 more source

Molecular Characterization and Epidemiology of Carbapenem‐Resistant Enterobacteriaceae Isolated from Pediatric Patients in Guangzhou, Southern China

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2023, Issue 1, 2023., 2023
Background. Carbapenem‐resistant Enterobacteriaceae (CRE) are spreading worldwide, posing a serious public health concern. However, the data on CRE strains that cause infections in children in Guangzhou remain limited. Therefore, this study aimed to investigate the epidemiology of CRE, drug resistance, and resistance mechanisms in children in Guangzhou,
Fei Gao, Zhile Xiong, Bingshao Liang, Zhenting Huang, Qiulian Deng, Jielin Wang, Huamin Zhong, Yan Long, Sufei Zhu, Matthew Gavino Donadu   +9 more
wiley   +1 more source

Extended‐spectrum β‐lactamase‐producing and carbapenem‐resistant Enterobacterales bloodstream infection after solid organ transplantation: Recent trends in epidemiology and therapeutic approaches

Transplant Infectious Disease, Volume 24, Issue 4, August 2022., 2022
Abstract Background Infections caused by multidrug‐resistant gram‐negative bacilli (MDR GNB), in particular extended‐spectrum β‐lactamase‐producing (ESBL‐E) and carbapenem‐resistant Enterobacterales (CRE), pose a major threat in solid organ transplantation (SOT).
Elena Pérez‐Nadales, Mario Fernández‐Ruiz, Belén Gutiérrez‐Gutiérrez, Álvaro Pascual, Jesús Rodríguez‐Baño, Luis Martínez‐Martínez, José María Aguado, Julian Torre‐Cisneros   +7 more
wiley   +1 more source

Outbreak of NDM-1– and OXA-181–Producing Klebsiella pneumoniae Bloodstream Infections in a Neonatal Unit, South Africa

Emerging Infectious Diseases, 2023
After an increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infections and associated deaths in the neonatal unit of a South Africa hospital, we conducted an outbreak investigation during October 2019–February 2020 and cross ...
Rindidzani E. Magobo, Husna Ismail, Michelle Lowe, Wilhelmina Strasheim, Ruth Mogokotleng, Olga Perovic, Stanford Kwenda, Arshad Ismail, Manala Makua, Abram Bore, Rose Phayane, Harishia Naidoo, Tanya Dennis, Makhosazane Ngobese, Wim Wijnant, Nelesh P. Govender   +15 more
doaj   +1 more source

Prevalence of insertion sequence elements in plasmids relating to mgrB gene disruption causing colistin resistance in Klebsiella pneumoniae

MicrobiologyOpen, Volume 11, Issue 1, February 2022., 2022
Klebsiella pneumoniae is the dominant species carrying colistin‐resistance inducing insertion sequence elements ISKpn25, ISKpn26, ISKpn14, and IS903B on plasmids. ISKpn25, ISKpn26, ISKpn14 bearing plasmids have a high carriage of carbapenemase genes and are associated with clinical source isolation relative to IS903B.
Stephen Mark Edward Fordham, Anna Mantzouratou, Elizabeth Sheridan   +2 more
wiley   +1 more source