Results 21 to 30 of about 1,952 (169)

Successful control of an extended-spectrum beta-lactamase-producing Klebsiella pneumoniae ST307 outbreak in a neonatal intensive care unit [PDF]

BMC Infectious Diseases, 2020
Background In this study, we evaluated the genetic relatedness of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KPN) isolates from an outbreak in a neonatal intensive care unit (NICU) in August 2017, We implemented an active ...
Eun-Hwa Baek, Se-Eun Kim, Sunjoo Kim, Seungjun Lee, Oh-Hyun Cho, Sun In Hong, Jeong Hwan Shin, Inyeong Hwang   +7 more
doaj   +5 more sources

A Klebsiella pneumoniae ST307 outbreak clone from Germany demonstrates features of extensive drug resistance, hypermucoviscosity, and enhanced iron acquisition [PDF]

Genome Medicine, 2020
Background Antibiotic-resistant Klebsiella pneumoniae are a major cause of hospital- and community-acquired infections, including sepsis, liver abscess, and pneumonia, driven mainly by the emergence of successful high-risk clonal lineages.
Stefan E. Heiden, Nils-Olaf Hübner, Jürgen A. Bohnert, Claus-Dieter Heidecke, Axel Kramer, Veronika Balau, Wolfgang Gierer, Stephan Schaefer, Tim Eckmanns, Sören Gatermann, Elias Eger, Sebastian Guenther, Karsten Becker, Katharina Schaufler   +13 more
doaj   +6 more sources

Outbreak of NDM-5-producing Klebsiella pneumoniae ST307: an emerging high-risk antimicrobial resistance clone in Shanghai, China

mSystems
The high-risk clone Klebsiella pneumoniae ST307, associated with various carbapenem resistance genes, exhibits a global distribution and prevalence. However, in China, it has remained sporadic and has rarely been detected.
Junying Zhu, Guangyu Wang, Min Li
doaj   +3 more sources

Detection of Delafloxacin Resistance Mechanisms in Multidrug-Resistant Klebsiella pneumoniae [PDF]

Antibiotics
Background: In this study, the mechanisms implicated in delafloxacin resistance in Klebsiella pneumoniae strains were investigated. Delafloxacin is a novel, broad-spectrum fluoroquinolone that has been approved for clinical application.
András Kubicskó, János Juhász, Katalin Kamotsay, Dora Szabo, Béla Kocsis   +4 more
doaj   +2 more sources

Outbreak investigation and genomic analysis reveal hidden transmission networks of KPC-2-producing Enterobacterales in a South Korean hospital [PDF]

Antimicrobial Resistance and Infection Control
Background We investigated a KPC-2-producing Enterobacterales (KPC-2 CPE) outbreak in a Korean hospital from July to September 2019, which subsided following enhanced surveillance and strict infection control.
Sun Hee Park, Seul Ki Ji, Soyoung Shin, Chulmin Park, Jeong-Ih Shin, Seung-Hyun Jung, Jung-Hyun Choi, Dong-Gun Lee   +7 more
doaj   +2 more sources

Multiple Benefits of Plasmid-Mediated Quinolone Resistance Determinants in Klebsiella pneumoniae ST11 High-Risk Clone and Recently Emerging ST307 Clone [PDF]

Frontiers in Microbiology, 2019
International high-risk clones of Klebsiella pneumoniae are among the most common nosocomial pathogens. Increased diversity of plasmid-encoded antimicrobial resistance genes facilitates spread of these clones causing significant therapeutic difficulties.
Judit Domokos, Ivelina Damjanova, Katalin Kristof, Balazs Ligeti, Balazs Ligeti, Bela Kocsis, Dora Szabo   +6 more
doaj   +3 more sources

Molecular epidemiology of carbapenemase-producing Klebsiella pneumoniae in Gauteng South Africa [PDF]

Scientific Reports
Klebsiella pneumoniae multidrug-resistant (MDR) high-risk clones drive the spread of antimicrobial resistance (AMR) associated infections, resulting in limited therapeutic options. This study described the genomic characteristics of K.
Kafilat T. Salvador-Oke, Johann D. D. Pitout, Gisele Peirano, Kathy-Anne Strydom, Chanel Kingsburgh, Marthie M. Ehlers, Arshad Ismail, Faustinos T. Takawira, Marleen M. Kock   +8 more
doaj   +2 more sources

Genomic surveillance reveals different transmission patterns between third-generation cephalosporin and carbapenem resistance in Klebsiella pneumoniae in the Comunidad Valenciana (Spain), 2018–2020 [PDF]

Antimicrobial Resistance and Infection Control
Background The emergence and spread of third-generation cephalosporins (3GC) and carbapenem-resistant Klebsiella pneumoniae pose a global critical challenge.
Neris García-González, Beatriz Beamud, Jordi Sevilla-Fortuny, Victoria Sánchez-Hellín, Inmaculada Vidal, Juan Carlos Rodríguez, Begoña Fuster, Nuria Tormo, Carme Salvador, Concepción Gimeno, Barbara Gomila-Sard, Salvador Giner, Olalla Martínez, Javier Colomina, David Navarro, Victoria Domínguez, on behalf of Networked Laboratory for the Surveillance of Antimicrobial Resistance of the Valencian Community, Fernando González-Candelas   +17 more
doaj   +2 more sources

The successful containment of a hospital outbreak caused by NDM-1-producing Klebsiella pneumoniae ST307 using active surveillance.

PLoS ONE, 2019
The worldwide dissemination of high-risk carbapenemase-producing Klebsiella pneumoniae clones has become a major threat to healthcare facilities.
Paola Bocanegra-Ibarias, Elvira Garza-González, Magaly Padilla-Orozco, Soraya Mendoza-Olazarán, Eduardo Pérez-Alba, Samantha Flores-Treviño, Ulises Garza-Ramos, Jesus Silva-Sánchez, Adrián Camacho-Ortiz   +8 more
doaj   +5 more sources

Epidemiological Genomics of Klebsiella pneumoniae isolates from hospitals across Colombia. [PDF]

NPJ Antimicrob Resist
Klebsiella pneumoniae is one of the most important nosocomial pathogens worldwide. In Colombia, K. pneumoniae has been identified as the second most frequent microbial etiologic agent of healthcare-associated infections.
Medina VA, García-Vega AS, Rodríguez F, Triviño-García ES, Robledo JA, Leal AL, Galvis JC, Reyes LF, Genomic Epidemiology of Antimicrobial Resistance Consortium (GEAR), Okeke IN, Couto N, Kumaran EA, Lewis-Woodhouse G, Argimon S, Arevalo SA, Underwood AP, Fargetton X, Aanensen DM, Donado-Godoy MP.   +18 more
europepmc   +3 more sources