Results 51 to 60 of about 1,531 (135)

Outbreak by KPC-62-producing ST307 Klebsiella pneumoniae isolates resistant to ceftazidime/avibactam and cefiderocol in a university hospital in Madrid, Spain [PDF]

, 2023
8 p.Objectives: Ceftazidime/avibactam and cefiderocol are two of the latest antibiotics with activity against a wide variety of Gram-negatives, including carbapenem-resistant Enterobacterales.
Pablo Sánchez, Raúl De
core   +1 more source

Klebsiella pneumoniae Glycoconjugate Vaccine Leads Based on Semi‐Synthetic O1 and O2ac Antigens

Angewandte Chemie, Volume 137, Issue 7, February 10, 2025.
Glycans resembling lipopolysaccharides of Klebsiella pneumoniae (K. pneumoniae) strains O1 and O2ac were chemically synthesized. The 27 glycans were used to screen the sera of infected patients and controls for antibody binding. The glycan array study identified epitopes for the development of semi‐synthetic glycoconjugate vaccines against K ...
Julinton Sianturi, Fabienne Weber, Rajat Kumar Singh, Tilman Lingscheid, Pinkus Tober‐Lau, Florian Kurth, Bettina C. Fries, Peter H. Seeberger   +7 more
wiley   +2 more sources

Pandemic Clones of CTX-M-15 Producing Klebsiella pneumoniae ST15, ST147, and ST307 in Companion Parrots

, 2022
Psittacine birds are commonly kept as companion birds and the maintenance of these birds in captivity may represent a zoonotic risk and contribute to the propagation of multidrug-resistant and β-lactamase extended-spectrum (ESBLs)-producing pathogens ...
Cunha, Marcos Paulo Vieira, Davies, Yamê Miniero, Gomes, Vasco Túlio Moura, Vasco Túlio Moura Gomes, Marcos Paulo Vieira Cunha, Terezinha Knöbl, Yamê Miniero Davies, Knöbl, Terezinha, Moreno, Luisa Zanoli, Andrea Micke Moreno, Dropa, Milena, Lincopan, Nilton, Sato, Maria Inês Zanoli, Maria Inês Zanoli Sato, Luisa Zanoli Moreno, Moreno, Andrea Micke, Milena Dropa, Nilton Lincopan   +17 more
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Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, Volume 13, Issue 42, 28 July 2026.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Risk factors for acquisition of colistin-resistant Klebsiella pneumoniae and expansion of a colistin-resistant ST307 epidemic clone in hospitals in Marseille, France, 2014 to 2017

, 2021
International audienceFrance is a low prevalence country for colistin resistance. Molecular and epidemiological events contributing to the emergence of resistance to colistin, one of the 'last-resort' antibiotics to treat multidrug-resistant Gram ...
Baron, Sophie Alexandra, Hadjadj, Linda, Dubourg, Gregory, Hamel, Mouna, Cassir, Nadim, Rolain, Jean-Marc, Saidani, Nadia   +6 more
core   +1 more source

Whole-genome sequencing of carbapenem-resistant Enterobacterales isolates and evaluation of hospital-acquired infections

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Multidrug-resistant organisms (MDROs) are increasingly implicated in nosocomial outbreaks worldwide. We evaluated whole-genome sequencing (WGS) as an adjunctive epidemiological tool to identify infection clusters and MDRO transmission in the ...
Leama Ajaka, Shandra Day, Christina Liscynesky, Nora Colburn, Christine Sun, Michael Sovic, Preeti Pancholi, Joan-Miquel Balada-Llasat, Heather Smith, Shashanka Murthy   +9 more
doaj   +1 more source

Co‐Occurrence of Resistance to Aminoglycosides and Carbapenems in Klebsiella pneumoniae: A Critical Threat to Public Health

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Antimicrobial resistance (AMR) in Klebsiella pneumoniae, especially the co‐occurrence of resistance to aminoglycosides and carbapenems, represents a serious threat to global public health. This study reviews the prevalence of this combined resistance, analyzes the underlying mechanisms, and evaluates its impact on clinical practice and public health ...
Rafael Artur de Queiroz Cavalcanti de Sa, Tainara Fernandes Dantas, Sérgio Costa Júnior, Karolayne Oliveira da Silva, Maria Cecília Ferreira Galindo, Amanda Vieira de Barros, John Eversong Lucena de Vasconcelos, Radosław Kowalski, Grażyna Kowalska, Rafal Rowinski, Henrique Douglas Melo Coutinho, Maria Betânia Melo Oliveira, Divakar Sharma   +12 more
wiley   +1 more source

Simultaneous Hospital Outbreaks of New Delhi Metallo-β-Lactamase-Producing Enterobacterales Unraveled Using Whole-Genome Sequencing

Microbiology Spectrum, 2022
Multidrug-resistant Enterobacterales, including carbapenemase producers, are currently spreading in health care facilities and the community. The Bichat Claude Bernard hospital in Paris faced a prolonged NDM-producing Enterobacterales (NDM-CPE) outbreak.
Stéphane Lo, Isabelle Lolom, Valérie Goldstein, Marie Petitjean, Emilie Rondinaud, Vincent Bunel-Gourdy, Alexy Tran Dinh, Paul-Henri Wicky, Etienne Ruppé, Camille d’Humières, Jean-Christophe Lucet, Laurence Armand-Lefèvre   +11 more
doaj   +1 more source

Antimicrobial Resistance, Virulence, and Genomic Characteristics of Klebsiella pneumoniae Isolated From Four Host Sources in Northeast China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Klebsiella pneumoniae is an important emerging pathogen leading to serious clinical outcomes as the multidrug‐resistant (MDR) isolates arise. While K. pneumoniae is a well‐known pathogen in human clinical settings, its risks in nonhuman hosts and potential for cross‐species transmission remain poorly understood. In this study, we performed whole‐genome
Qiu Xu, Cuilong Fan, Yaowei Liu, Xiaofeng Lu, Wei Song, Susu Du, Yao Zhu, Fang Xie, Wanjiang Zhang, Zhong Peng   +9 more
wiley   +1 more source

Changing Epidemiology of KPC Producing Klebsiella pneumoniae in Argentina: Emergence of Hypermucoviscous ST25 and High Risk Clone ST307 [PDF]

, 2019
Objectives: To assess the epidemiological features of 76 Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) isolates recovered from three hospitals in Buenos Aires, Argentina, during 2015–2017.
Alfonso, Claudia, Cejas, Daniela, Elena, Alan Xavier, De Paulis, Adriana, Fernández Canigia, Liliana, Nuñez, Daiana Guevara, Magariños, Francisco, Gutkind, Gabriel Osvaldo, Platero, Priscila Sevillano, Berger, María Alejandra, Radice, Marcela Alejandra   +10 more
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