Results 61 to 70 of about 1,952 (169)

Multiplicity of blaKPC genes and pKpQIL plasmid plasticity in the development of ceftazidime-avibactam and Meropenem coresistance in Klebsiella pneumoniae sequence type 307 [PDF]

, 2023
In 2021, Klebsiella pneumoniae sequence type 307 (ST307) strains causing pulmonary and bloodstream infections identified in a hospital in Rome, Italy, reached high levels of resistance to ceftazidime-avibactam (CZA).
Arcari, Gabriele, Bruno, Francesco, Capitani, Valerio, Carattoli, Alessandra, Garcia-Fernandez, Aurora, Gentile, Giuseppe, Polani, Riccardo, Raponi, Giammarco, Sacco, Federica, Santilli, Stefania, Villa, Laura   +10 more
core   +2 more sources

Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae. [PDF]

, 2017
BACKGROUND: Klebsiella pneumoniae is a gram-negative bacterial species capable of occupying a broad range of environmental and clinical habitats. Known as an opportunistic pathogen, it has recently become a major causative agent of clinical infections ...
Anun, Suthatip, Blane, Beth, Chantratita, Narisara, Moradigaravand, Danesh, Paksanont, Suporn, Parkhill, Julian, Peacock, Sharon J, Runcharoen, Chakkaphan, Thammachote, Jeeranan   +8 more
core   +3 more sources

Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy [PDF]

, 2015
A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014.
BONURA, Celestino, Carattoli, A., Endimiani, A., Feudi, C., Fortini, D., MAMMINA, Caterina, Pires, J., Villa, L.   +7 more
core   +3 more sources

CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3 [PDF]

, 2022
Carbapenemases; High-risk clones; Whole genome sequencingCarbapenemasas; Clones de alto riesgo; Secuenciación del genoma completoCarbapenemases; Clons d'alt risc; Seqüenciació del genoma sencerObjectives: CARB-ES-19 is a comprehensive, multicenter ...
Cano, María E., Cañada-Garcia, Javier E., Delgado-Valverde, Mercedes, Gijón, Desirèe, Gonzalez Lopez, Juan Jose, Larrosa Escartin, María Nieves, Moure Garcia, Zaira, Sola-Campoy, Pedro Juan   +7 more
core   +18 more sources

Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of bla NDM-1 in India, Sweden, and the United Kingdom [PDF]

, 2012
Clinical isolates of Klebsiella pneumoniae producing NDM-1 carbapenemase from India (n = 22), the United Kingdom (n = 13), and Sweden (n = 4) were subjected to multilocus sequence typing (MLST), automated repetitive sequence-based PCR (rep-PCR ...
Froding, Inga, Giske, Christian G., Hasan, Chowdhury, Livermore, David, Toleman, Mark, Turlej-Rogacka, Agata, Walsh, Timothy R., Woodford, Neil   +7 more
core   +2 more sources

Contact-Dependent Growth Inhibition Proteins in Acinetobacter baylyi ADP1 [PDF]

, 2018
Bacterial contact-dependent growth inhibition (CDI) systems are two-partner secretion systems in which toxic CdiA proteins are exported on the outer membrane by cognate transporter CdiB proteins. Upon binding to specific receptors, the C-terminal toxic
de Gregorio, Eliana, Di Nocera, Pierpaolo, Esposito, Eliana Pia, Zarrilli, Raffaele   +3 more
core   +1 more source

Molecular epidemiology and mechanisms of tigecycline resistance in carbapenem‐resistant Klebsiella pneumoniae isolates

Journal of Clinical Laboratory Analysis, Volume 34, Issue 12, December 2020., 2020
We introduce the mechanisms of tigecycline resistance in carbapenem‐resistant K pneumoniae (CRKP) isolates. The transcriptional activator MarA‐mediated overexpression of AcrAB efflux pump plays an important role in the emergence of tigecycline resistance in CRKP isolates. Abstract Background The emergence and transmission of tigecycline‐ and carbapenem‐
Yumi Park, Qute Choi, Gye Cheol Kwon, Sun Hoe Koo   +3 more
wiley   +1 more source

pKBuS13, a KPC-2-Encoding Plasmid from Klebsiella pneumoniae Sequence Type 833, Carrying Tn4401b Inserted into an Xer Site-Specific Recombination Locus [PDF]

, 2015
Here, we report the first detection of a Klebsiella pneumoniae carbapenemase 2 (KPC-2)-producing Klebsiella pneumoniae strain belonging to sequence type 833 (ST833), collected in an Italian hospital from a patient coming from South America.
Bressan, Raffaela, Busetti, Marina, Dolzani, Lucilla, Garbari, Luigi, Gionechetti, Fabrizia, Knezevich, Anna, Lagatolla, Cristina, Petix, Vincenzo, Tonin, Enrico Angelo   +8 more
core   +1 more source

Klebsiella pneumoniae Glycoconjugate Vaccine Leads Based on Semi‐Synthetic O1 and O2ac Antigens

Angewandte Chemie, Volume 137, Issue 7, February 10, 2025.
Glycans resembling lipopolysaccharides of Klebsiella pneumoniae (K. pneumoniae) strains O1 and O2ac were chemically synthesized. The 27 glycans were used to screen the sera of infected patients and controls for antibody binding. The glycan array study identified epitopes for the development of semi‐synthetic glycoconjugate vaccines against K ...
Julinton Sianturi, Fabienne Weber, Rajat Kumar Singh, Tilman Lingscheid, Pinkus Tober‐Lau, Florian Kurth, Bettina C. Fries, Peter H. Seeberger   +7 more
wiley   +2 more sources

Characterisation of and risk factors for extended-spectrum β-lactamase producing Enterobacterales (ESBL-E) in an equine hospital with a special reference to an outbreak caused by Klebsiella pneumoniae ST307:CTX-M-1

Acta Veterinaria Scandinavica, 2022
Background Extended-spectrum β-lactamase producing Enterobacterales (ESBL-E) are important causative agents for infections in humans and animals. At the Equine Veterinary Teaching Hospital of the University of Helsinki, the first infections caused by ...
Katariina Thomson, Katarina Eskola, Marjut Eklund, Kristiina Suominen, Merita Määttä, Jouni Junnila, Suvi Nykäsenoja, Kati Niinistö, Thomas Grönthal, Merja Rantala   +9 more
doaj   +1 more source