Results 31 to 40 of about 1,154,439 (299)
Nature Communications, 2021 Inhibitor of Differentiation 1 (ID1) is an oncogene for colorectal cancer. Here, the authors show a complex interplay between nuclear receptor Nur77 and Transforming Growth Factor-β (TGFβ) to regulate ID1 expression at both transcriptional and post ...
Boning Niu +9 more
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Connectomics in high throughput [PDF]
Nature Methods, 2020 BRICseq provides access to brain-wide connectivity and can be combined with functional and transcriptomic studies for a comprehensive view of neuronal circuitry.
openaire +2 more sources
Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study
Metals, 2023 This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui +2 more
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A High Throughput Workflow Environment for Cosmological Simulations [PDF]
, 2012 The next generation of wide-area sky surveys offer the power to place extremely precise constraints on cosmological parameters and to test the source of cosmic acceleration.
Becker, Matthew R. +8 more
core +2 more sources
High-throughput Technology and High-throughput Factory
Nihon Kessho Gakkaishi, 2003 Structural Genomics has launched over the world including National Project of Protein Structural and Functional Analysis in Japan in a post-genomic era. It remains many bottlenecks to determine the protein structures with SR protein crystallography based on full-genome sequence information in high throughput manner.
Masashi MIYANO +2 more
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SLAS DiscoveryAnimal testing for drug discovery is expensive and the decision to test a compound in an in vivo model should be carefully considered. In addition, the FDA Modernization Act has resulted in the allowance of alternatives to animal models for testing the ...
N. Miranda Nebane +7 more
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, 2015 Standard protocols are available in order to apply Phenotype MicroArray (PM) technology to characterize different groups of microorganisms. Nevertheless, there is the need to pay attention to several crucial steps in order to obtain high-quality and reproducible data from PM, such as the choice of the Dye mix, the type and concentration of the carbon ...
Carlo, Viti +4 more
openaire +3 more sources
High-throughput viscosity determinations [PDF]
Review of Scientific Instruments, 2008 A new high-throughput viscosimeter device was designed, built, and tested allowing measurement of the viscosity of 100 different solutions in a single experiment using the falling sphere approach. Using the corrected Stokes’ law, viscosities obtained by the HT device were compared to viscosities of the same solutions obtained on a conventional ...
Ma, Jing +2 more
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High-throughput Binding Affinity Calculations at Extreme Scales [PDF]
, 2018 Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily ...
Balasubramanian, Vivek +7 more
core +3 more sources
BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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