Results 31 to 40 of about 1,151,593 (279)

A High Throughput Workflow Environment for Cosmological Simulations [PDF]

open access: yes, 2012
The next generation of wide-area sky surveys offer the power to place extremely precise constraints on cosmological parameters and to test the source of cosmic acceleration.
Becker, Matthew R.   +8 more
core   +2 more sources

Connectomics in high throughput [PDF]

open access: yesNature Methods, 2020
BRICseq provides access to brain-wide connectivity and can be combined with functional and transcriptomic studies for a comprehensive view of neuronal circuitry.
openaire   +2 more sources

Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study

open access: yesMetals, 2023
This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui   +2 more
doaj   +1 more source

High-throughput Technology and High-throughput Factory

open access: yesNihon Kessho Gakkaishi, 2003
Structural Genomics has launched over the world including National Project of Protein Structural and Functional Analysis in Japan in a post-genomic era. It remains many bottlenecks to determine the protein structures with SR protein crystallography based on full-genome sequence information in high throughput manner.
Masashi MIYANO   +2 more
openaire   +2 more sources

A high-throughput human tissue model for respiratory viruses: Automating the use of human airway epithelial tissues for faster drug discovery

open access: yesSLAS Discovery
Animal testing for drug discovery is expensive and the decision to test a compound in an in vivo model should be carefully considered. In addition, the FDA Modernization Act has resulted in the allowance of alternatives to animal models for testing the ...
N. Miranda Nebane   +7 more
doaj   +1 more source

High-throughput Binding Affinity Calculations at Extreme Scales [PDF]

open access: yes, 2018
Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily ...
Balasubramanian, Vivek   +7 more
core   +2 more sources

High-Throughput Phenomics

open access: yes, 2015
Standard protocols are available in order to apply Phenotype MicroArray (PM) technology to characterize different groups of microorganisms. Nevertheless, there is the need to pay attention to several crucial steps in order to obtain high-quality and reproducible data from PM, such as the choice of the Dye mix, the type and concentration of the carbon ...
Carlo, Viti   +4 more
openaire   +3 more sources

Genomic analysis of 61 Chlamydia psittaci strains reveals extensive divergence associated with host preference

open access: yesBMC Genomics, 2023
Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse   +7 more
doaj   +1 more source

High-throughput detection of metal contamination in HTS outputs

open access: yesSLAS Discovery, 2022
Large compound libraries utilised for HTS often include metal contaminated compounds which can interfere with assay signal or target biology, and therefore appear as hits.
Corinne Molyneux   +5 more
doaj   +1 more source

Measuring reproducibility of high-throughput experiments

open access: yes, 2011
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative discoveries ...
Bickel, Peter J.   +3 more
core   +1 more source

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