Results 121 to 130 of about 485,334 (314)

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice

open access: yesNature Communications, 2019
Targeted CRISPR libraries expand the use of genetic screens across experimental conditions. Here, the authors develop a method for generating and analysing small scale custom CRISPR libraries and use it in the human and livestock pathogen Toxoplasma ...
Joanna Young   +11 more
doaj   +1 more source

Discussion of: Brownian distance covariance

open access: yes, 2013
We discuss briefly the very interesting concept of Brownian distance covariance developed by Sz\'{e}kely and Rizzo [Ann. Appl. Statist. (2009), to appear] and describe two possible extensions.
Kosorok, Michael R.
core   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

High Throughput Virtual Screening with Data Level Parallelism in Multi-core Processors

open access: yes, 2013
Improving the throughput of molecular docking, a computationally intensive phase of the virtual screening process, is a highly sought area of research since it has a significant weight in the drug designing process.
Prabuddha, Rahal   +2 more
core   +1 more source

Synergistic Roles of FAHD‐1 and PYC‐1 in Mitochondrial Function, Behavior, and Longevity in C. elegans

open access: yesAdvanced Biology, EarlyView.
FAHD‐1 and PYC‐1 catalyze opposing mitochondrial reactions that regulate oxaloacetate homeostasis in Caenorhabditis elegans. Using single and double knockouts, this study reveals that both enzymes shape locomotion, reproduction, respiration, and lifespan.
Riccardo Giaquinta   +3 more
wiley   +1 more source

Micropleated Nanofibrous Filters for High‐Efficiency Submicron Aerosol Filtration: A Comparative Study with Chemical, Biological, Radiological, and Nuclear Gas Mask Filters

open access: yesAdvanced Engineering Materials, EarlyView.
This study presents micropleated filters manufactured by needleless electrospinning. Nanofibers are deposited onto uniaxially pre‐stretched substrates that contract upon release, forming densely packed micropleats. This architecture increases effective surface area without enlarging the filter size, achieving quality factors comparable to those of ...
Aleksandr Fadeev   +6 more
wiley   +1 more source

What Do Large Language Models Know About Materials?

open access: yesAdvanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer   +2 more
wiley   +1 more source

Experimental Analysis and Physics‐Based Analytical Model on Twisted and Coiled Artificial Muscles

open access: yesAdvanced Engineering Materials, EarlyView.
Twisted and coiled artificial muscles made from silver‐coated nylon fibers are investigated through experiments and analytical modeling. The actuators achieve contractions up to 19.3% and specific work of 8 kJ kg−1, though efficiency remains limited (≈0.15%) by thermal losses.
Salvatore Garofalo   +3 more
wiley   +1 more source

Patient-derived organoid elucidates the identical clonal origin of bilateral breast cancer with diverse molecular subtypes

open access: yesFrontiers in Oncology
Bilateral breast cancer (BBC), an infrequent breast cancer subtype, has primarily been studied in terms of incidence, prognosis, and through comparative analysis of synchronous (SBBC) and metachronous (MBBC) manifestations.
Zhongbin Han   +14 more
doaj   +1 more source

Recent Advancements in Bulk Processing of Rare‐Earth‐Free Hard Magnetic Materials and Related Multiscale Simulations

open access: yesAdvanced Engineering Materials, EarlyView.
This article provides an overview of recent advancements in bulk processing of rare‐earth‐free hard magnetic materials. It also addresses related simulation approaches at different scales. The research on rare‐earth‐free magnetic materials has increased significantly in recent years, driven by supply chain issues, environmental and social concerns, and
Daniel Scheiber, Andrea Bachmaier
wiley   +1 more source

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