Results 11 to 20 of about 485,334 (314)
Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model
Cancer Cell International, 2022 Purpose Radiotherapy is one of the essential treatment modalities for nasopharyngeal carcinoma (NPC), however, radioresistance still poses challenges.
Yanhua Fang +6 more
doaj +1 more source
Cell Discovery, 2023 How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription.
Xinyu Zhang +7 more
doaj +1 more source
High throughput biodegradation-screening test to prioritize and evaluate chemical biodegradability [PDF]
, 2017 Comprehensive assessment of environmental biodegradability of pollutants is limited by the use of low throughput systems. These are epitomized by the Organisation for Economic Cooperation and Development (OECD) Ready Biodegradability Tests (RBTs), where ...
Martin, Timothy J. +5 more
core +2 more sources
Computational screening of magnetocaloric alloys [PDF]
, 2020 An exciting development over the past few decades has been the use of high-throughput computational screening as a means of identifying promising candidate materials for a variety of structural or functional properties.
Bocarsly, Joshua D +2 more
core +2 more sources
RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes. [PDF]
, 2017 Synthetic biology and metabolic engineering seek to re-engineer microbes into living foundries for the production of high value chemicals. Through a design-build-test cycle paradigm, massive libraries of genetically engineered microbes can be constructed
Abate, Adam +8 more
core +1 more source
Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]
, 2011 Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core +1 more source
Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening [PDF]
, 2017 Lowering total tau levels is an attractive therapeutic strategy for Alzheimer's disease and other tauopathies. High-throughput screening in neurons derived from human induced pluripotent stem cells (iPSCs) is a powerful tool to identify tau-targeted ...
Chen, Robert +12 more
core +3 more sources
High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing [PDF]
, 2018 This is the peer reviewed version of the following article:Ioanna D. Styliari, et al, ‘High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing’, Macromolecular Materials and Engineering, (2018), which has been published in ...
Alexander, Cameron +16 more
core +4 more sources
A high-throughput screening method for determining the substrate scope of nitrilases [PDF]
, 2014 Nitrile compounds are intermediates in the synthesis of pharmaceuticals such as atorvastatin. We have developed a chromogenic reagent to screen for nitrilase activity as an alternative to Nessler's reagent. It produces a semi-quantifiable blue colour and
Black, Gary +5 more
core +1 more source
Frontiers in Pharmacology, 2022 Aims: Reports of hepatitis in children during the coronavirus disease 2019 (COVID-19) pandemic garnered worldwide attention. The most probable culprits are adenovirus and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Yanhua Fang +5 more
doaj +1 more source