Results 21 to 30 of about 1,236,846 (314)

Computational high-throughput screening of alloy nanoclusters for electrocatalytic hydrogen evolution

npj Computational Materials, 2021
Here, we report a density functional theory (DFT)-based high-throughput screening method to successfully identify a type of alloy nanoclusters as the electrocatalyst for hydrogen evolution reaction (HER).
Xinnan Mao, Lu Wang, Yafeng Xu, Pengju Wang, Youyong Li, Jijun Zhao   +5 more
semanticscholar   +1 more source

High throughput biodegradation-screening test to prioritize and evaluate chemical biodegradability [PDF]

, 2017
Comprehensive assessment of environmental biodegradability of pollutants is limited by the use of low throughput systems. These are epitomized by the Organisation for Economic Cooperation and Development (OECD) Ready Biodegradability Tests (RBTs), where ...
Martin, Timothy J., Goodhead, Andrew K., Acharya, Kishor, Head, Ian M., Snape, Jason, Davenport, Russell J.   +5 more
core   +2 more sources

Optimised techniques for high-throughput screening of differentiated SH-SY5Y cells and application for neurite outgrowth assays

Scientific Reports, 2021
Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the molecular and cellular processes involved in disorders of the nervous system.
Anusha Dravid, Brad Raos, D. Svirskis, Simon J. O'Carroll   +3 more
semanticscholar   +1 more source

Computational screening of magnetocaloric alloys [PDF]

, 2020
An exciting development over the past few decades has been the use of high-throughput computational screening as a means of identifying promising candidate materials for a variety of structural or functional properties.
Bocarsly, Joshua D, Garcia, Christina A. C, Seshadri, Ram   +2 more
core   +2 more sources

Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening [PDF]

, 2017
Lowering total tau levels is an attractive therapeutic strategy for Alzheimer's disease and other tauopathies. High-throughput screening in neurons derived from human induced pluripotent stem cells (iPSCs) is a powerful tool to identify tau-targeted ...
Chen, Robert, Chen, Xu, Ding, Sheng, Gan, Li, Karch, Celeste M, Liu, Kai, Ludwig, Connor, Meyer-Franke, Anke, Sohn, Peter Dongmin, Tracy, Tara E, Wang, Chao, Ward, Michael E, Xie, Min   +12 more
core   +3 more sources

Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]

, 2011
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core   +1 more source

High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing [PDF]

, 2018
This is the peer reviewed version of the following article:Ioanna D. Styliari, et al, ‘High‐Throughput Miniaturized Screening of Nanoparticle Formation via Inkjet Printing’, Macromolecular Materials and Engineering, (2018), which has been published in ...
Alexander, Cameron, Alexander, Morgan R., Burley, Jonathan, Cavanagh, Robert, Conte, Claudia, Couturaud, Benoit, Garnett, Martin, Gordhan, Dipak, Hook, Andrew, Huesler, Amanda, Limo, Marion, Nieto-Orellana, Alejandro, Pearce, Amanda, Styliari, Ioanna Danai, Suksiriworapong, Jiraphong, Taresco, Vincenzo, Williams, Phil   +16 more
core   +4 more sources

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E., Dai, Jennifer B., Daigle, Renee, Forman, Stuart A., Halpin, Elizabeth S., Jounaidi, Youssef, Marte-Oquendo, Francisco, Porco, John A., Schaus, Scott E., Trilles, Richard, Xu, Wenqing, Yang, Xiaoxuan, Yu, Buwei   +12 more
core   +1 more source

Potential protective benefits of Schisandrin B against severe acute hepatitis in children during the COVID-19 pandemic based on a network pharmacology analysis

Frontiers in Pharmacology, 2022
Aims: Reports of hepatitis in children during the coronavirus disease 2019 (COVID-19) pandemic garnered worldwide attention. The most probable culprits are adenovirus and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Yanhua Fang, Lingling Zhang, Zhe Wang, Ruoyu Wang, Ruoyu Wang, Shanshan Liang   +5 more
doaj   +1 more source

Codelivery of HBx-siRNA and Plasmid Encoding IL-12 for Inhibition of Hepatitis B Virus and Reactivation of Antiviral Immunity

Pharmaceutics, 2022
Chronic hepatitis B is a critical cause of many serious liver diseases such as hepatocellular carcinoma (HCC). The main challenges in hepatitis B treatment include the rebound of hepatitis B virus (HBV)-related antigen levels after drug withdrawal and ...
Yan Mu, Xiao-He Ren, Di Han, Ying-Ying Guan, Pei-Ling Liu, Si-Xue Cheng, Hong Liu   +6 more
doaj   +1 more source