Results 81 to 90 of about 118,745 (262)

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

Corrigendum: Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma

Frontiers in Oncology, 2020
Yixing Gao, Bao Liu, Bao Liu, Lan Feng, Lan Feng, Binda Sun, Binda Sun, Shu He, Shu He, Yidong Yang, Yidong Yang, Gang Wu, Gang Wu, Guoji E, Guoji E, Chang Liu, Chang Liu, Yuqi Gao, Yuqi Gao, Erlong Zhang, Erlong Zhang, Bo Zhu   +21 more
doaj   +1 more source

In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions

Frontiers in Immunology
BackgroundHypoxia plays a pivotal role in modulating immune responses, especially in neutrophils, which are essential components of the innate immune system.
Yi Ye, Yi Ye, Yi Ye, Yanjun Wang, Yanjun Wang, Yanjun Wang, Yanjun Wang, Qiying Xu, Qiying Xu, Qiying Xu, Qiying Xu, Juanli Liu, Juanli Liu, Juanli Liu, Juanli Liu, Ziqi Yang, Tana Wuren, Tana Wuren, Tana Wuren, Ri-Li Ge, Ri-Li Ge, Ri-Li Ge   +21 more
doaj   +1 more source

Much more than their fangs: Macroscopic anatomy of the brain of Bothrops moojeni Hoge 1966 (Squamata, Serpentes, Viperidae)

The Anatomical Record, EarlyView.
Abstract Neuroanatomical research has progressed considerably in several vertebrate lineages, yet studies of reptilian brain morphology remain markedly underdeveloped. Here we provide the first description of macroscopic brain anatomy and its ontogeny in the viperid Bothrops moojeni, based on a sample of seven individuals.
Paula Araújo, Júlio César Costa de Souza, Angele Martins   +2 more
wiley   +1 more source

Hypoxia promotes progression of cervical cancer by modulating the ATXN3-enhanced P53 stability or STAT5 phosphorylation

Cell Death Discovery
This study examines hypoxia’s role in regulating ATXN3 (ATXN3) across cervical cancer subtypes and its impact on tumor progression. We analyzed ATXN3 expression in clinical samples and cell lines (C33A, HeLa, SiHa), assessing proliferation/migration ...
Rong Zhang, Shengjun Chai, Fengjuan Zhang, Jiaming Lai, Rui Wang, Guocai Xu, Xiaoxia Fan, Botong Li, Chunmei Cai   +8 more
doaj   +1 more source

Clade‐wide morphological and functional variation of the sauropsid columella

The Anatomical Record, EarlyView.
Abstract The columella (=stapes) is the middle ear bone of reptiles that transmits vibrations from the environment to the inner ear. It has been shown to exhibit extensive interspecific morphological disparity in several clades; however, its morphological variation and associated functional consequences remain poorly described.
John Peacock, Serjoscha W. Evers, Tiago R. Simões, Garth M. Spellman, Daniel J. Field   +4 more
wiley   +1 more source

Prevalence of gallstone disease and its association with altitude and ethnicity among employee health check-upers in the Qinghai-Tibet Plateau

BMC Gastroenterology
Objective This study aimed to investigate the prevalence of gallstone disease among health check-upers (employees) in the Qinghai-Tibet Plateau and clarify the independent effects of altitude, ethnicity, and their interaction on gallstone disease risk ...
Shenggui Qi, Li Li, Yuhua Yan, Gengdeng, Xiaofeng Ma, Airong Yang, Hongguang Fan   +6 more
doaj   +1 more source

Balancing mechanics and metabolism: Elevational variation in the microanatomy of hummingbird flight muscle

The Anatomical Record, EarlyView.
Abstract Factors varying along elevational gradients impose strong aerodynamic and physiological constraints on powered flight, yet the internal microanatomical variation associated with elevational context in animals under such conditions remains poorly understood.
Juan Camilo Ríos‐Orjuela, Juliana Novoa‐Páramo, Maria Juliana Villalba Patiño, Zayra Viviana Garavito‐Aguilar, Alejandro Rico‐Guevara, Carlos Daniel Cadena   +5 more
wiley   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

Prospecting of Architectural Features Using LiDAR‐UAV Technology, Deep Neural Networks and Visualization Techniques: A Case Study in Kuélap and Cambolín (NW Peru)

Archaeological Prospection, EarlyView.
ABSTRACT High‐resolution and accurate synoptic images of terrestrial topography, even in densely forested areas, have proven valuable for archaeology by enabling the identification and characterization of relief patterns associated with ancient human activities. This study presents a novel approach that integrates digital terrain models (DTMs) obtained
Jhon A. Zabaleta‐Santisteban, Rolando Salas López, Angel J. Medina‐Medina, Katerin M. Tuesta‐Trauco, Abner S. Rivera‐Fernandez, Nerci M. Noriega‐Salazar, José A. Sánchez‐Vega, Teodoro B. Silva‐Melendez, Marlen A. Grandez‐Alberca, Jhonsy O. Silva‐López, Nilton B. Rojas‐Briceño, Manuel Oliva‐Cruz, Alexander Cotrina‐Sanchez, Elgar Barboza   +13 more
wiley   +1 more source