Results 51 to 60 of about 67,791 (260)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Development of a new and sensitive method for the detection of pork adulteration in gelatin and other highly processed food products

Food Additives & Contaminants: Part A, 2021
Porcine adulteration has become a major concern amongst communities including Muslims and Jews. Reliable detection of the presence of porcine DNA in gelatin and highly processed food samples is essential for Halal and kosher food control. In this study, a forensic approach involving DNA isolation and real-time polymerase chain reaction (PCR) was ...
Mediha Esra Altuntop Yayla, Canan Ekinci Doğan   +1 more
openaire   +3 more sources

Astrofood, Priorities and Pandemics: Reflections of an Ultra-Processed Breakfast Program and Contemporary Dysbiotic Drift

Challenges, 2017
Recognizing the importance of nutrition as part of the grand challenges faced by humanity—the current epidemic of non-communicable diseases (NCDs), sustainability and maintenance of Planetary Health—the United Nations (UN) has declared 2016–2025 the ...
Alan C. Logan, Susan L. Prescott
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Relationships between Childhood Food Experiences and the Use of Food Restrictions in Young Adulthood—A Cross-Sectional Study

Proceedings
Parental feeding practices are a source of childhood food experiences (CFE), which can influence behavior in youth and later in adulthood. This study aimed to assess the relationship between CFE related to restrictions, restrained eating, and restricting
Marzena Jeżewska-Zychowicz, Aleksandra Małachowska   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Vegan diet, processed foods, and body weight: a secondary analysis of a randomized clinical trial

Nutrition & Metabolism
Low-fat plant-based diets cause weight loss in clinical trials. However, many foods are highly processed, raising the question as to their effect on body weight.
Hana Kahleova, Tatiana Znayenko-Miller, Arathi Jayaraman, Giulianna Motoa, Laura Chiavaroli, Richard Holubkov, Neal D. Barnard   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Towards sustainable diets: addressing saturated fats and environmental impacts of processed foods

Bulletin of the National Research Centre
Sustainable food production encompasses environmental, economic, and social dimensions. Rapid urbanization and industrialization have significantly altered dietary patterns, leading to increased consumption of convenience foods that are often highly ...
Akshita Sharma, Khalid Mehmood Wani
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source