Comparison of 2-Aminobenzamide, Procainamide and RapiFluor-MS as Derivatizing Agents for High-Throughput HILIC-UPLC-FLR-MS N-glycan Analysis [PDF]
Frontiers in Chemistry, 2018 Rising awareness of the universal importance of protein N-glycosylation governs the development of further advances in N-glycan analysis. Nowadays it is well known that correct glycosylation is essential for proper protein function, which emanates from ...
Olga Gornik, Gordan Lauc, Toma Keser
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Pregnancy-related changes in the canine serum N-glycosylation pattern studied by Rapifluor HILIC-UPLC-FLR-MS [PDF]
Scientific ReportsCanine reproduction differs from that of many other domestic animals, and increased knowledge on biochemical changes during canine pregnancy is important for investigations of infertility or subfertility.
Margareta Ramström +3 more
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A Novel Ultra‐Performance Liquid Chromatography‐Electrospray Ionisation‐Tandem Mass Spectrometry Method for Quantification of Imeglimin in Human Plasma: Application to a Bioequivalence Study [PDF]
Analytical Science AdvancesThe pharmaceutical market has recently witnessed the advent of a novel tetrahydrotriazene molecule belonging to the new pharmacological class “Glimins”, named Imeglimin (IMG).
Mina Wadie +5 more
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Establishment of an N-Glycan Profiling Method for Three ERT Enzymes Used in Gaucher Disease Therapy [PDF]
MoleculesN-glycosylation, particularly terminal mannose exposure, is a critical quality attribute affecting macrophage targeting and the clinical efficacy of enzyme replacement therapy for Gaucher disease.
Jinliang Chen +6 more
doaj +2 more sources
Differences in canine serum N-glycosylation pattern during infection and pregnancy [PDF]
Scientific ReportsDiagnosis of inflammatory disorders during canine pregnancy is complicated by changes caused by pregnancy. The total glycosylation pattern of body fluids reflects cellular status in health and disease.
Margareta Ramström +4 more
doaj +2 more sources
A Benchtop Approach To Measuring S-AdenosylMethionine Metabolite Levels Using HILIC UPLC-MS [PDF]
Journal of the Kentucky Academy of Science, 2019 Erin Strome
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Immunoglobulin G N-glycosylation predicts long-term risk of ischemic stroke: a nested case-control study [PDF]
Journal of Translational MedicineBackground Ischemic stroke (IS) ranks as the leading cause of disability and the second cause of mortality in adults worldwide. This investigation aimed to describe the fingerprint of immunoglobulin G (IgG) N-glycans and feature of circulating ...
Shuyu Sun +14 more
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International Journal of Analytical Chemistry, 2022 A new method was developed for the identification and determination of L-ergothioneine in cosmetics based on ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
Li Liu +8 more
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Scientific Reports, 2022 Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including infections, in humans.
Laudine M. C. Petralia +10 more
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Untargeted metabolomics analysis on kidney tissues from mice reveals potential hypoxia biomarkers
Scientific Reports, 2023 Chronic hypoxia may have a huge impact on the cardiovascular and renal systems. Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to identify new biomarkers.
Muhammad Imran Sajid +7 more
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