Results 21 to 30 of about 5,381 (125)
NMR联用HILIC-UPLC-MS/MS测定TNBS诱导的结肠炎大鼠尿液和血浆代谢物变化
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的基于非靶标和靶标代谢组学技术，探讨三硝基苯磺酸（TNBS）诱导的结肠炎模型大鼠尿液以及血浆中内源性代谢物的变化。方法16只雄性SD大鼠随机分成对照组和模型组，每组8只，对模型组大鼠给予TNBS灌肠以建立实验性大鼠结肠炎模型。利用核磁共振氢谱（1H NMR）检测两组大鼠尿液代谢物，同时联用HILIC模式超高效液相色谱串联三重四级杆质谱（HILIC-UPLC-MS/MS）测定以上大鼠尿液以及血浆中氨基酸水平，并通过多元变量统计方法对代谢组学数据进行分析。结果同对照组相比，1H ...
刘雯 +7 more
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Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome
Metabolites, 2019 Most human proteins are glycosylated. Attachment of complex oligosaccharides to the polypeptide part of these proteins is an integral part of their structure and function and plays a central role in many complex disorders.
Karsten Suhre +7 more
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Frontiers in Immunology, 2020 Select residues in the biantennary sugar moiety attached to the fragment crystallizable of immunoglobulin G (IgG) antibodies can modulate IgG effector functions.
Anja Schaffert +15 more
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International Journal of Analytical Chemistry, 2021 Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) has become the main method for the detection and analysis of food additives because of its good separation, high selectivity, and high sensitivity.
Yanqin Sun +3 more
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Rapid determination of matrine and oxymatrine in honey
Shipin yu jixie, 2022 Objective: This study aimed to establish a new method for the determination of matrine and oxymatrine in honey by UPLC-MS/MS. Methods: The honey was dissolved in water, and the liquid-liquid extraction pretreatment technology was adopted.
JING Hui-hua +5 more
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Urine Metabolome during Parturition
Metabolites, 2020 In recent years, some studies have described metabolic changes during human childbirth labor. Metabolomics today is recognized as a powerful approach in a prenatal research context, since it can provide detailed information during pregnancy and it may ...
Federica Gevi +6 more
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Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease. [PDF]
PLoS ONE, 2015 This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients attending the memory clinic: cases of mild cognitive impairment (MCI; n = 16), cases of MCI ...
Stewart F Graham +8 more
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Rapid Determination of Five Alkaloids in Catering Crayfish by QuEChERS-UPLC-MS/MS
Shipin gongye ke-ji, 2023 In this study, a method for the determination of morphine, codeine, nacodine, papaverine and tibain residues in catering crayfish by ultra-high-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was established.
Ling YU, Lihua SONG
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Biomolecules, 2022 Background and aim: Glycomic alterations serve as biomarker tools for different diseases. The present study aims to evaluate the diagnostic capability of serum N-glycosylation to identify alcohol risk drinking in comparison with standard markers. Methods:
Róisín O’Flaherty +7 more
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Molecules, 2018 Quality control of Chinese herbal tea remains a challenge due to our poor knowledge of their complex chemical profile. This study aims to investigate the chemical composition of one of the best-selling and famous brand of beverage in China, Wanglaoji ...
Chao-Zhan Lin +6 more
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