Results 21 to 30 of about 5,403 (145)
Glycoconjugate Journal, 2020 N-glycan analyses may serve uncovering disease-associated biomarkers, as well as for profiling distinctive changes supporting diagnosis of genetic disorders of glycan biosynthesis named congenital disorders of glycosylation (CDG). Strategies based on liquid chromatography (LC) preferentially coupled to electrospray ionization (ESI) - mass spectrometry (
Angela Messina +8 more
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Pharmacology Research & Perspectives, 2019 Creatine transporter deficiency (CTD) is a metabolic disorder resulting in cognitive, motor, and behavioral deficits. Cyclocreatine (cCr), a creatine analog, has been explored as a therapeutic strategy for the treatment of CTD.
Kirill Gorshkov +13 more
doaj +1 more source
Determination of atmospheric organosulfates using HILIC chromatography with MS detection [PDF]
Atmospheric Measurement Techniques, 2015 Measurements of organosulfates in ambient aerosols provide insight to the extent of secondary organic aerosol (SOA) formation from mixtures of biogenic gases and anthropogenic pollutants.
A. P. S. Hettiyadura +6 more
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Establishment and Optimization of an Untargeted Metabolomics Method for the Analysis of Breast Milk Based on Ultra-high Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry [PDF]
Shipin KexueIn this study, an untargeted metabolomics method for the analysis of breast milk samples from different lactation stages was established using ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS).
JING Mengna, FU Jieyu, ZHAO Junying, LIU Yanpin, QIAO Weicang, CHEN Lijun
doaj +1 more source
The Neuroinflammatory Phenotype in a Mouse Model of Gulf War Illness is Unrelated to Brain Regional Levels of Acetylcholine as Measured by Quantitative HILIC-UPLC-MS/MS [PDF]
Toxicological Sciences, 2018 Many veterans of the 1991 Persian Gulf War (GW) returned with a chronic multisymptom illness that has been termed Gulf War Illness (GWI). Previous GWI studies have suggested that exposure to acetylcholinesterase inhibitors (AChEIs) in theater, such as sarin and/or pesticides, may have contributed to the symptomatology of GWI.
Julie V Miller +7 more
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Comparative HILIC-UPLC analysis of immunoglobulin G N-glycome from saliva and plasma [PDF]
, 2022 Immunoglobulin G (IgG) is the most abundant antibody in the blood and plays a critical role in host immune defence against infectious pathogens. IgG glycosylation is known to modulate IgG effector functions and is involved in the development and progression of disease.
Radovani Trbojević, Barbara +2 more
openaire
Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome
Metabolites, 2019 Most human proteins are glycosylated. Attachment of complex oligosaccharides to the polypeptide part of these proteins is an integral part of their structure and function and plays a central role in many complex disorders.
Karsten Suhre +7 more
doaj +1 more source
Frontiers in Immunology, 2020 Select residues in the biantennary sugar moiety attached to the fragment crystallizable of immunoglobulin G (IgG) antibodies can modulate IgG effector functions.
Anja Schaffert +15 more
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International Journal of Analytical Chemistry, 2021 Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) has become the main method for the detection and analysis of food additives because of its good separation, high selectivity, and high sensitivity.
Yanqin Sun +3 more
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Rapid determination of matrine and oxymatrine in honey
Shipin yu jixie, 2022 Objective: This study aimed to establish a new method for the determination of matrine and oxymatrine in honey by UPLC-MS/MS. Methods: The honey was dissolved in water, and the liquid-liquid extraction pretreatment technology was adopted.
JING Hui-hua +5 more
doaj +1 more source