Results 61 to 70 of about 13,123 (252)

The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cells, 2020
Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC).
R. F. Helderman, Daan R Löke, J. Verhoeff, H. Rodermond, Gregor G W van Bochove, M. Boon, Sanne van Kesteren, J. J. Garcia Vallejo, H. P. Kok, P. Tanis, N. Franken, J. Crezee, A. Oei   +12 more
semanticscholar   +1 more source

Survival advantage of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced gastric cancer: experience from a Western tertiary referral center

Langenbeck's archives of surgery (Print), 2021
Selection criteria and prognostic factors for patients with advanced gastric cancer (AGC) undergoing cytoreductive surgery (CRS) plus hyperthermic intra-operative peritoneal chemotherapy (HIPEC) have not been well defined and the literature data are not ...
F. Rosa, F. Galiandro, R. Ricci, D. Di Miceli, F. Longo, G. Quero, A. Tortorelli, S. Alfieri   +7 more
semanticscholar   +1 more source

Prospective case‐control cohort analysis of two‐day/two‐stage pelvic exenteration surgery: Safety, feasibility, acceptability and medium‐term outcomes

Colorectal Disease, Volume 28, Issue 1, January 2026.
Abstract Aim Pelvic exenteration (PE) is the only curative option for extensive pelvic cancers. Advances have facilitated increasingly complex resectional and reconstructive components, including per‐operative oncological adjuncts such as intraoperative radiotherapy.
Charles T. West, Yousif Salem, Siddharth Jain, Lewis Matthews, Julian Smith, Marios Nicolaou, Hideaki Yano, Malcolm A. West, Alex H. Mirnezami   +8 more
wiley   +1 more source

Effect of hyperthermia on improving neutrophil restoration after intraperitoneal chemotherapy

International Journal of Hyperthermia, 2019
Purpose: Intraperitoneal (IP) chemotherapy has several benefits but also can have severe hematologic side effects. We compared the effects of hyperthermic intraperitoneal chemotherapy (HIPEC) and conventional IP chemotherapy on bone marrow suppression ...
Wan-Chun Huang, Chao-Chih Wu, Yun-Ting Hsu, Chih-Long Chang   +3 more
doaj   +1 more source

Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers

Journal of Surgical Oncology, Volume 132, Issue 5, Page 789-809, October 2025.
ABSTRACT Peritoneal malignancy often indicates disruptions in multiple physiological systems resulting from widespread cancer. The heterogenous origin and dynamic nature of peritoneal cancer make it difficult to treat with standard approaches that fit into guidelines.
Ada I. Ozcan, Arianexys Aquino López, Mary K. McKenna, Malcolm K. Brenner, Alastair M. Thompson   +4 more
wiley   +1 more source

Transcriptomic Profiles for Elucidating Response of Bladder Intracavitary Hyperthermic Perfusion Chemotherapy in High‐Risk Nonmuscular Invasive Bladder Cancer

Cancer Medicine
Background Bladder intracavitary hyperthermic perfusion chemotherapy (HIPEC) is a promising treatment for non‐muscular invasive bladder cancer (NMIBC). However, the molecular mechanisms underlying the response to HIPEC remain poorly understood.
Zhicheng Huang, Tianhui Zhang, Jinghua Pan, Guihao Zhang, Linjun Jiang, Huiming Jiang, Pei Wan, Ying Peng, Wenchao Zou, Qinghua Liu, Nanhui Chen   +10 more
doaj   +1 more source

Fear of cancer recurrence in peritoneal malignancy patients following complete cytoreductive surgery (CCRS) and hyperthermic intraperitoneal chemotherapy (HIPEC): an observational study protocol [PDF]

, 2022
Rayan Taher, Sophia Stanford, Norman J. Carr, Nancy Vanderpuye, Kandiah Chandrakumaran   +4 more
openalex   +1 more source

Effect of HIPEC on Peritoneal Recurrence in Peritoneal Metastasis Treated With Cytoreductive Surgery: A Systematic Review

Frontiers in Oncology, 2021
Background Peritoneal metastasis (PM) is a late-stage manifestation of intra-abdominal malignancies. The current standard of care indicates that cure can only be achieved with cytoreductive surgery (CRS) which is often indicated with concurrent adjuvant ...
D. Yap, J. Wong, Qiu Xuan Tan, J. W. Tan, C. Chia, C. Ong   +5 more
semanticscholar   +1 more source

Closed‐Incision Negative Pressure Therapy: Scoping Review and Multidisciplinary Consensus Recommendations of the Spanish Observatory of Infection in Surgery

International Wound Journal, Volume 22, Issue 10, October 2025.
ABSTRACT Surgical site infections (SSI) and surgical site complications (SSC) significantly impact surgery outcomes, increasing hospital stays and mortality rates, and negatively affecting patients' quality of life. Closed‐incision negative pressure therapy (ciNPT) emerged as a prophylactic strategy to reduce these complications.
Josep M. Badia, Inés Rubio‐Pérez, Carlos Morales‐Pérez, José Bueno‐Lledó, Laura M. Rodríguez‐Lorenzo, Joan Sancho, Oliver Marín‐Peña, Susana López, Jaume Masià, José M. Balibrea   +9 more
wiley   +1 more source

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

CA: A Cancer Journal for Clinicians, Volume 75, Issue 5, Page 436-460, September/October 2025.
Abstract High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer, accounting for approximately 70% of all ovarian cancer cases and contributing significantly to the high mortality rates associated with this disease.
Pawel Kordowitzki, Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner, Ioana Elena Braicu, Jalid Sehouli   +6 more
wiley   +1 more source