Results 41 to 50 of about 120,668 (359)

The Role of Differentially Expressed miRNAs and Potential miRNA-mRNA Regulatory Network in Prostate Cancer Progression and Metastasis [PDF]

, 2020
Purpose: Aberrant expression of microRNAs (miRNAs) has been discovered in prostate cancer progression however their function is not well understood, thereby further investigation is required to understand the importance of underlying mechanisms and their
Arisan, E.D., Arisan, E.D., Freitas, I.L., Freitas, I.L., Pazoki, K., Pazoki, K., Rahim, S., Rahim, S., Uysal Onganer, P., Uysal Onganer, P.   +9 more
core   +1 more source

Tata Kelola Demokrasi: Membangkitkan Semangat Pengawasan, Pengetahuan, Kesadaran, dan Partisipasi Politik Mahasiswa Melalui Program Sosialisasi

Jurnal Kewarganegaraan
The research method used in this research is associative quantitative research. The population of this study were all students of San Agustin Hippo Catholic University who participated in the election monitoring socialization program in 2023, totaling ...
Apolonius Yonas, Oxtapianus Tawarik, Sapomo Sapomo, Pebrianus Hendri   +3 more
doaj   +1 more source

Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease

Cells, 2020
In order to ascertain their external environment, cells and tissues have the capability to sense and process a variety of stresses, including stretching and compression forces.
Mathias Cobbaut, Simge Karagil, Lucrezia Bruno, Maria Del Carmen Diaz de la Loza, Francesca E Mackenzie, Michael Stolinski, Ahmed Elbediwy   +6 more
doaj   +1 more source

Hepatic Hippo signaling inhibits development of hepatocellular carcinoma [PDF]

Clinical and Molecular Hepatology, 2020
Primary liver cancer is one of the most common cancer worldwide. Hepatocellular carcinoma (HCC) in particular, is the second leading cause of cancer deaths in the world.
Yuchen Liu, Xiaohui Wang, Yingzi Yang
doaj   +1 more source

Evaluating the role of the Hippo pathway in the onset and disease progression of the SOD1 mouse model of amyotrophic lateral sclerosis [PDF]

, 2016
The Hippo pathway is a cell signaling pathway involved in organ size regulation and tumorigenesis in mammals. This pathway regulates the activity of Yes-associated protein (YAP), a transcriptional coactivator which binds to the transcription factor TEAD ...
Granucci, Eric
core   +1 more source

Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]

, 2018
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core   +1 more source

How Toll Met Hippo [PDF]

Developmental Cell, 2016
Toll and Hippo are two seemingly disparate pathways that regulate innate immunity and tissue growth, respectively. Reporting recently in Cell, Liu et al. (2016) tie them together by demonstrating that microbial infection activates Toll, which then signals to both pathways to modulate the antimicrobial response.
Nie, Yingchao, Ip, Y. Tony
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Syntactic Phrases Analysis in Disney Wish Movie

Jurnal Simki Pedagogia
This research analyzed syntactic phrases that are used in the dialogue of the Disney Wish movie. This research aims to find out the types of phrases and the most common phrases that are used by the main characters in the Disney Wish movie.
Desi Kumala Sari Antonia, Tuminah Tuminah   +1 more
doaj   +1 more source