Results 131 to 140 of about 36,476 (254)

Adolescents' Experiences of Weight‐Related Bullying in the School Setting—A Qualitative Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Obesity is a stigmatised disease, and weight‐related bullying is the most common form of victimisation. This study aimed to provide a nuanced understanding of adolescents’ experiences of such victimisation and related interventions. Methods Data were collected between April and October 2025 through semi‐structured interviews and analysed ...
Emelie Andersson, Nicole Mpatsiaris Riboe, Kajsa Järvholm   +2 more
wiley   +1 more source

Drilling the Marathousa palaeo‐lake in Greece (Peloponnese): inferring the environmental context of a Middle Pleistocene archaeological site

Boreas, EarlyView.
The Megalopolis Basin is located in the central Peloponnese (Greece), a region that is situated along one of the primary Pleistocene biogeographical corridors for intracontinental hominin migration. The basin comprises several hundred metres of Plio‐Pleistocene sediments alternating between clastics and lignites.
Ines J. E. Bludau, Bernd Wagner, Uwe Kirscher, Maria Schindler, Charlotte Zachow, Johannes Schmidt, Niklas Leicher, Giovanni Muttoni, Serena Perini, Vangelis Tourloukis, Eleni Panagopoulou, Panagiotis Karkanas, Katerina Harvati, Annett Junginger   +13 more
wiley   +1 more source

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

Cancer Science, EarlyView.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source

Signaling by Hippo

Reactome - a curated knowledgebase of biological pathways, 2012
openaire   +1 more source

AKR1C3 Binds β‐Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

Cancer Science, EarlyView.
In this study, we show that aldo‐keto reductase family 1 member C3 (AKR1C3), a protein highly expressed in ferroptosis resistant hepatocellular carcinoma cells, acts as an enzyme‐independent scaffold protein by promoting the nuclear export of β‐transducin repeat protein (β‐TrCP) and its binding to transferrin receptor (TFRC) in an enzyme‐independent ...
Lei Qi, Jingyi Hua, Di Pan, Wanwan Yang, Geng Tian, Fangyu Ye, Lingxiang Liu, Yuhan Mao, Qinglong Guo, Haopeng Sun, Li Zhao   +10 more
wiley   +1 more source

Decreased Expression of FAT4 Promotes Multiple Myeloma Proliferation and Migration by Targeting the Hippo/YAP Pathway

Cancer Science, EarlyView.
This study provides the first comprehensive characterization of the functional impact, and mechanistic role of FAT4 in MM. Our findings highlight the tumor‐suppressive role of FAT4 in MM and uncover a novel mechanism by which FAT4 regulates the Hippo/YAP pathway.
Lina Zhang, Na Shen, Xin Cheng, Qinglin Shi, Lijuan Chen, Xuxing Shen   +5 more
wiley   +1 more source

Canonical and noncanonical Hippo signaling in C. elegans. [PDF]

Genetics
Huynh L, Fakieh RA, Hendrix C, Powell RT, Reiner DJ.   +4 more
europepmc   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

The Hippo signaling pathway in pediatric brain tumors: molecular mechanisms and therapeutic opportunities. [PDF]

Cancer Metastasis Rev
Papanikolaou MA, Gargalionis AN, Adamopoulos C, Piperi C.   +3 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source