Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Chidamide and Anlotinib act synergistically in Jurkat cells by inhibiting the Hippo signaling pathway. [PDF]
Ma T +6 more
europepmc +1 more source
Doctrine, Narrative and the Formation of Christian Identity: A Conversation with Alister McGrath
Abstract This article offers a critical and appreciative response to Alister McGrath’s The Nature of Christian Doctrine, exploring the formation of doctrine as a dynamic communal process rooted in Scripture, liturgy and historical context. It highlights McGrath’s analogy between doctrinal development and scientific method, emphasising the search for a ...
Frances Margaret Young
wiley +1 more source
EIF4A3-induced circUBAC2 promotes lung cancer progression via regulation of the Hippo signaling pathway. [PDF]
Meng F +12 more
europepmc +1 more source
Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez +1 more
wiley +1 more source
GTPBP2 inactivates Hippo signaling to promote triple-negative breast cancer cell malignancy. [PDF]
Zhao X +6 more
europepmc +1 more source
Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis +54 more
wiley +1 more source
Abstract The African seahorse Hippocampus algiricus has been considered restricted to the eastern Atlantic coast of Africa, with occasional records in Macaronesian archipelagos. The species is currently classified as Vulnerable by the International Union for Conservation of Nature (IUCN).
Jorge Hernández‐Urcera +3 more
wiley +1 more source
Correction: The impact of inhibiting the Hippo signaling pathway effector molecule YAP1 on in vitro glioblastoma and glioblastoma stem cells. [PDF]
Ozates NP +5 more
europepmc +1 more source
Postcranial anatomy of the Miocene hippopotamoids of Toros‐Menalla, Chad
We establish a framework for the identification of postcranial remains in hippopotamoids by describing and comparing for the first time two late Miocene hippopotamoids from Toros‐Menalla, Chad (Hexaprotodon garyam, an early hippopotamid, and Libycosaurus bahri, the last African anthracothere) with the common hippopotamus.
Lorenzo Scribano +4 more
wiley +1 more source

