Alterations in the Hippo Signaling Pathway During Adenogenesis Impairment in Postnatal Mouse Uterus. [PDF]
İnanç İ +4 more
europepmc +1 more source
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati +13 more
wiley +1 more source
Correction: Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway. [PDF]
Zhang HB, Zeng Y, Wang G.
europepmc +1 more source
Saikosaponin A from Radix Bupleuri inhibited colorectal cancer HCT116 cells with low toxicity. SSA induced S/G2‐M cell cycle arrest and triggered autophagy via mTOR inhibition. SSA suppressed metastasis by blocking PI3K/AKT signaling pathway. SSA significantly reduced tumor growth without apparent toxicity.
Xiu‐Xiu Zhang +7 more
wiley +1 more source
Knockdown of PVT1 inhibits cell proliferation in luminal and basal-like breast cancer subtypes by activating LATS2/Hippo signaling pathway. [PDF]
Zhang HB, Zeng Y, Wang G.
europepmc +1 more source
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley +1 more source
E-cadherin inhibits the proliferation and migration of human colorectal cancer cells through Hippo signaling pathway. [PDF]
Wang Z +6 more
europepmc +1 more source
Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He +9 more
wiley +1 more source
Photothermal Hyperthermia Suppresses Liver Tumor Growth Via Hippo Signaling Pathway-Dependent Inhibition of Cell Proliferation and Induction of Apoptosis. [PDF]
Li J +11 more
europepmc +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source

