Hippo Signaling Pathway in Colorectal Cancer: Modulation by Various Signals and Therapeutic Potential. [PDF]
Mohammadpour S +7 more
europepmc +1 more source
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa +17 more
wiley +1 more source
Hippo signaling pathway regulates Ebola virus transcription and egress. [PDF]
Liang J +4 more
europepmc +1 more source
Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava +9 more
wiley +1 more source
Tanshinone IIA alleviates tri-ortho-cresyl phosphate-induced ovarian damage through Hippo signaling pathway activation in mice. [PDF]
Ma Z +9 more
europepmc +1 more source
Mechanobiology in Stem Cell‐Based Bioprinting
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley +1 more source
Targeting the YAP/TAZ Hippo signaling pathway for oral cancer treatment. [PDF]
Thiruvengadam M.
europepmc +1 more source
Whole Blood Transcriptomic Analysis of Sickle Cell Trait
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson +12 more
wiley +1 more source
Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway. [PDF]
Umegaki T +4 more
europepmc +1 more source
The Regulation and Function of Hippo/YAP Pathway in Cancer
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh +3 more
wiley +1 more source

