Results 171 to 180 of about 101,099 (274)

The methyltransferase N6amt1 regulates hippocampal neurogenesis through 6 mA modification of Txnrd3 DNA. [PDF]

Cell Mol Life Sci
Wu Y, Ma W, Li Q, Li Y, Xie L, Kong X, Chen S, Wang Q, Xuan A.   +8 more
europepmc   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, Volume 309, Issue 2, Page 451-470, February 2026.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source

Associations of Dietary Decanoic Acid Intake With Cognitive Function in the Elderly and the Mediating Effects of Hypertension and Diabetes: An Analysis From NHANES 2011–2014

Brain and Behavior, Volume 16, Issue 2, February 2026.
This study included elderly people aged 60 and above in the NHANES 2011–2014 cycle. The research indicated that increased dietary decanoic acid intake was associated with better cognitive function in the elderly, among which diabetes and hypertension were statistically associated with a partial mediating effect, although causality cannot be inferred ...
Huangxin Zhu, Qingan Fu, Juanjuan Hu, Yihong Wu, Jun Min   +4 more
wiley   +1 more source

Aberrant mRNA splicing and impaired hippocampal neurogenesis in <i>Grin2b</i> mutant mice. [PDF]

iScience
Farsi Z, Nicolella A, Simmons SK, Shin W, Kang M, Lee G, Kwon MJ, Brenner KS, Picard I, Shepard N, Misri D, Perzel Mandell KA, Levin JZ, Kim E, Sheng M.   +14 more
europepmc   +1 more source

Association Between Peripheral IL‐6 Levels in the Acute Stage of Stroke and Poststroke Depression: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 2, February 2026.
This is a meta‐analysis on the relationship between IL‐6 concentration in the acute phase of stroke and poststroke depression. Higher peripheral IL‐6 concentrations in the acute stage of stroke are closely related to the risk of PSD; collecting samples within 1 day after stroke onset and evaluating depression post discharge are recommended.
Hongmin Gong, Jiaqin Yuan, Min Li, Deqi Xiong, Fayang Ling, Mei Liu, Yan Hu, Shouqiang Wang   +7 more
wiley   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

Fecal microbiota transplantation promotes Wnt3a-mediated hippocampal neurogenesis in a rat model of chronic cerebral hypoperfusion. [PDF]

J Transl Med
Su SH, Lu DD, Wu YF, Huang XS, Zhang L.
europepmc   +1 more source

Hydrogen‐Mediated Activation of the Nrf2/HO‐1 Signaling Pathway Improves Cognitive Impairment in Sleep‐Deprived Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Hydrogen enhances memory and learning capabilities in sleep‐deprived mice by activating the Nrf2/HO‐1 signaling pathway, while suppressing neuronal damage, oxidative stress, and inflammatory responses. ABSTRACT Aims This study investigated the effects of hydrogen (H2) on cognitive impairment in sleep‐deprived mice mediated by the nuclear factor ...
QiFan Xiao, ShiRui Zhou, Bin Tang, YuQing Zhu   +3 more
wiley   +1 more source

Human adult hippocampal neurogenesis in health and disease. [PDF]

Aging Brain
Alonso-Moreno MC, Gallardo-Caballero M, Prádanos-Senén AV, Llorens-Martín M.   +3 more
europepmc   +1 more source

β‐Asarone Attenuates Neuroinflammation of Alzheimer's Disease by Activating Autophagy and Suppressing NLRP3 Inflammasome Assembly

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
β‐amyloid activates microglia via the TLR/NF‐κB pathway and primes the NLRP3 inflammasome, driving neuroinflammation. β‐asarone counteracts this by activating autophagy, which degrades NLRP3 components and inhibits inflammasome assembly. This reduces IL‐1β maturation, suppresses cytokine release, and alleviates neuronal damage and cognitive deficits in
Zhiwei Xu, Wanying Xu, Jinxin He, Jiahui Qian, Hui Wang, Changyu Li, Xiaojie Zhou   +6 more
wiley   +1 more source