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Hippocampal neurogenesis and depression.
Novartis Foundation symposium, 2008Various chronic antidepressant treatments increase adult hippocampal neurogenesis, but the functional importance of this phenomenon remains unclear. Using radiological and genetic methods, we show that disrupting neurogenesis blocks behavioural responses to antidepressants.
Amar, Sahay, René, Hen
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A computational principle for hippocampal learning and neurogenesis
Hippocampus, 2005In the three decades since Marr put forward his computational theory of hippocampal coding, many computational models have been built on the same key principles proposed by Marr: sparse representations, rapid Hebbian storage, associative recall and consolidation.
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Adult Hippocampal Neurogenesis
2010Abstract In the dentate gyrus of mammals, including humans, adult hippocampal neurogenesis lifelong generates one single type of excitatory neurons, new granule cell neurons, which contribute to the mossy fiber connection between the dentate gyrus and area CA3.
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Adult hippocampal neurogenesis and its impairment in Alzheimer’s disease
Zoological Research, 2022Thomas A Kim, Shaoyu Ge
exaly