Results 171 to 180 of about 56,531 (215)
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Neuropeptides and hippocampal neurogenesis
Neuropeptides, 2013Hippocampal neurogenesis is important for modulating the behavioural responses to stress and for certain forms of learning and memory. The mechanisms underlying the necessary coupling of neuronal activity to neural stem/progenitor cell (NSPC) function remain poorly understood. Within the dentate subgranular stem cell niche, local interneurons appear to
M J, Zaben, W P, Gray
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Hippocampal neurogenesis and forgetting
Trends in Neurosciences, 2013The hippocampus is thought to automatically encode all experience, yet the vast majority of our experiences are not remembered later. Although psychological theories have postulated the existence of decay processes for declarative memory, the corresponding neurobiological mechanisms are unknown.
Paul W, Frankland +2 more
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The interplay of neurovasculature and adult hippocampal neurogenesis
Neuroscience Letters, 2021 The subgranular zone of the dentate gyrus provides a local microenvironment (niche) for neural stem cells. In the adult brain, it has been established that the vascular compartment of such niches has a significant role in regulating adult hippocampal neurogenesis.
Thomas A Kim, Shaoyu Ge
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Stress and hippocampal neurogenesis
Biological Psychiatry, 1999The dentate gyrus of the hippocampal formation develops during an extended period that begins during gestation and continues well into the postnatal period. Furthermore, the dentate gyrus undergoes continual structural remodeling in adulthood. The production of new granule neurons in adulthood has been documented in a number of mammalian species ...
E, Gould, P, Tanapat
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Hippocampal Neurogenesis: A Matter of Survival
American Journal of Psychiatry, 2007The hippocampus has long been known to play a prominent role in establishing new memories. More recently, the hippocampus has been implicated in several psychiatric illnesses (e.g., Alzheimer’s disease, schizophrenia, depression) and may even play a role in the traumatic memories central to PTSD.
Diane C, Lagace +2 more
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Neurogenesis in hippocampal slice cultures
Molecular and Cellular Neuroscience, 2004A major challenge in studying neurogenesis in the adult brain is gaining access to neural stem cells for experimental manipulation. We developed an approach utilizing mouse hippocampal organotypic cultures to characterize neurogenesis under controlled conditions.
Raineteau O +4 more
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Adult hippocampal neurogenesis in depression
Nature Neuroscience, 2007The development of new treatments for depression is predicated upon identification of neural substrates and mechanisms that underlie its etiology and pathophysiology. The heterogeneity of depression indicates that its origin may lie in dysfunction of multiple brain regions.
Amar, Sahay, Rene, Hen
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