Results 201 to 210 of about 101,099 (274)

Oroxylum indicum ameliorates D-galactose-induced aging related memory impairments via enhancing rat hippocampal neurogenesis. [PDF]

Sci Rep
Tanrangka N, Prajit R, Kaewngam S, Anosri T, Sae-Foo W, Aranarochana A, Sritawan N, Sirichoat A, Putalun W, Wigmore P, Welbat JU.   +10 more
europepmc   +1 more source

Adolescent Vitamin D Supplementation Reverses Neuroplasticity and Motivational Deficits Induced by Developmental Alcohol Exposure and Early‐Life Stress

International Journal of Developmental Neuroscience, Volume 86, Issue 1, February 2026.
Adolescent vitamin D supplementation reverses behavioural and neuroplastic impairments induced by early‐life alcohol exposure and maternal separation in rats. Postnatal ethanol exposure (PND 4–10) and maternal separation stress (PND 2–14) led to motivational deficits and altered hippocampal plasticity.
Anelise Pereira Alves, Claudia Daniele Bianco, Clarice Mariano Fernandes, Ian Carlos Hübner, Patricia S. Brocardo   +4 more
wiley   +1 more source

Parvalbumin Interneuron-Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker. [PDF]

Adv Sci (Weinh)
Yan H, Wang Y, Deng X, Wu S, Pan Y, Du J, Yu M, Liu B, Wang H, Zhang Z, Chen J, Chen S, Wang Y, Walker T, Bartlett P, Ju J, Hou ST.   +16 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Chronic α5-GABA-A Receptor Potentiation Promotes Mouse Adult Hippocampal Neurogenesis. [PDF]

Hippocampus
Prevot TD, Marcotte M, David DJ, Mendez-David I, Mian MY, Cook JM, Guilloux JP, Sibille E.   +7 more
europepmc   +1 more source

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Oral Administration of Astrocyte-Targeted Natural Antioxidants Suppress NOX4-Driven Neuroinflammation and Restore Hippocampal Neurogenesis in MPTP-Induced Parkinson's Disease Mouse Model. [PDF]

Nutrients
Jo M, Kim CY, Ko K, Choi S, Kim J, Park K, Yi IJ, Nahm SS, Kim K, Kim W, Yi SS.   +10 more
europepmc   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

Melatonin as an Alleviator in Decabromodiphenyl Ether-Induced Aberrant Hippocampal Neurogenesis and Synaptogenesis: The Role of Wnt7a. [PDF]

Biomolecules
Shen J, Gao L, Gao J, Wang L, Yan D, Wang Y, Meng J, Li H, Chen D, Wu J.   +9 more
europepmc   +1 more source

Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss

Aging Cell, Volume 25, Issue 2, February 2026.
Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli, Lucía Casares‐Crespo, Elena Juárez‐Escoto, Helena Mira   +3 more
wiley   +1 more source