Results 91 to 100 of about 330,244 (384)

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation

Journal of Neuroinflammation, 2016
BackgroundHistamine is an amine widely known as a peripheral inflammatory mediator and as a neurotransmitter in the central nervous system. Recently, it has been suggested that histamine acts as an innate modulator of microglial activity.
S. M. Rocha, Tatiana Saraiva, A. Cristovao, R. Ferreira, T. Santos, Marta Esteves, Cláudia Saraiva, Goun Je, L. Cortes, J. Valero, G. Alves, A. Klibanov, Yoon-Seong Kim, L. Bernardino   +13 more
semanticscholar   +1 more source

Comparative analysis of short‐term and long‐term LL‐37‐induced rosacea‐like mouse models: Histopathological features and inflammatory immune responses

Animal Models and Experimental Medicine, EarlyView.
The aim of this study was to improve the long‐term LL‐37 mouse model and compare the disease manifestations and pathophysiology of short‐term and long‐term LL‐37‐induced rosacea‐like models. The results show that the long‐term LL‐37 induced mouse model provides a practical animal model for further study of the pathological mechanism of severe rosacea ...
Yiling Wu, Chuanxi Zhang, Hui Jin, Ruiping Zheng, Tian Li, Fuyu Jin, Yaqian Li, Xuemin Gao, Hong Xu, Zhongqiu Wei, Jie Yang   +10 more
wiley   +1 more source

Histamine Promotes Pseudomonas aeruginosa Biofilm Formation and Renders P. aeruginosa Biofilms More Resistant to Gentamicin and Azithromycin

Medical Principles and Practice
Introduction: Pseudomonas aeruginosa biofilms contribute to the persistent presence of this bacterium in the cystic fibrosis airways. P. aeruginosa produces histamine in vitro and expresses histamine receptors.
Karim Dib
doaj   +1 more source

Urinary and faecal N-methylhistamine concentrations do not serve as markers for mast cell activation or clinical disease activity in dogs with chronic enteropathies [PDF]

, 2014
This study sought to correlate faecal and urinary N-methylhistamine (NMH) concentrations with resting versus degranulated duodenal mast cell numbers in dogs with chronic enteropathies (CE), and investigate correlations between intestinal mast cell ...
Allenspach, K, Anfinsen, K P, Berghoff, N, Priestnall, S L, Steiner, J M, Suchodolski, J S   +5 more
core   +3 more sources

Therapeutic targeting of myeloid cells in liver fibrosis: Mechanisms and clinical prospects

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the origin, recruitment, and differentiation regulation mechanisms of myeloid cells in driving hepatic fibrosis progression. By targeting these three critical phases, potential therapeutic strategies for liver fibrosis can be explored.
Yue Wang, Yiming Liu, Dan Chen, Leiming Liu, Leimin Sun, Lingling Zhang   +5 more
wiley   +1 more source

Systematic review of the subcutaneous air pouch model using monosodium urate and calcium pyrophosphate and recommendations for studying crystal‐related arthropathies

Animal Models and Experimental Medicine, EarlyView.
Simplified schematic for generation of the subcutaneous air pouch model in the rodent. On day 0 and 4, air is injected into the subcutaneous space on the dorsal surface of the rodent to generate a cavity analogous to a synovial joint. On day 6, monosodium urate (MSU) or calcium pyrophosphate (CPP) crystals are injected into the pouch to stimulate ...
Wenu Hewage, Josif Vidimce, Ryan G. Shiels, Michael Morgan, Andrew C. Bulmer   +4 more
wiley   +1 more source

Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]

, 2018
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core   +2 more sources

Effect of Different Cooking Methods on Histamine Levels in Selected Foods

Annals of Dermatology, 2017
Background Histamine in food is known to cause food poisoning and allergic reactions. We usually ingest histamine in cooked food, but there are few studies about the influence of cooking method on the histamine level.
B. Chung, S. Park, Y. Byun, Jee Hee Son, Y. Choi, Yong Se Cho, Hye One Kim, C. Park   +7 more
semanticscholar   +1 more source

Pengaruh Penyiangan Dan Suhu Penyimpanan Terhadap Mutu Kimiawi, Mikrobiologis Dan Organoleptik Ikan Tongkol (Auxis Tharzard, Lac) [PDF]

, 2007
Ikan tongkol merupakan salah satu bahan pangan yang dikonsumsi masyarakat dan jika dibiarkanpada suhu kamar, maka terjadi proses penurunan mutu menjadi busuk.
Adiputra, N. (N), Arka, I. B. (I), Suranaya Pandit, I G, Suryadhi, N. T. (N)   +3 more
core  

Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals? [PDF]

, 2015
The spread of "obesity epidemic" and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a large research effort to find novel mechanisms controlling feeding
Gaetani, Silvana, Passani, Maria B., Provensi, Gustavo, Romano, Adele, Tempesta, Bianca   +4 more
core   +2 more sources