Results 121 to 130 of about 288,678 (341)

Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus. [PDF]

, 2018
Recently, we discovered a novel cDNA encoding the precursor of a small secretory protein, neurosecretory protein GL (NPGL), in the hypothalamic infundibulum of chickens. NPGL plays an important role in the regulation of growth and feeding.
Bentley, George, Bessho, Yuki, Furumitsu, Megumi, Iwakoshi-Ukena, Eiko, Kato, Masaki, Kriegsfeld, Lance, Shikano, Kenshiro, Tachibana, Tetsuya, Taniuchi, Shusuke, Ukena, Kazuyoshi   +9 more
core   +3 more sources

Metabolomics Assessment of the Mitigation of Lead‐Induced Inflammation in Adult Zebrafish (Danio rerio) by a Fermented Soybean Extract

Food Safety and Health, EarlyView.
Fermented soybean extract (FSE) at 50 mg/L has the potential to mitigate lead (Pb) toxicity (5 mg/L) observed in the zebrafish model. This study offers insights into food intervention in toxicology. ABSTRACT This study investigated the potential of fermented soybean extract (FSE) as an alternative therapy for lead (Pb) toxicity, without chelation side ...
Siok‐Geok Chong, Intan Safinar Ismail
wiley   +1 more source

Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo [PDF]

, 2008
Endothelial barrier dysfunction is a hallmark of many severe pathologies, including sepsis or atherosclerosis. The cardiovascular hormone atrial natriuretic peptide (ANP) has increasingly been suggested to counteract endothelial leakage.
Bihari, Peter, Bubik, Martin F., Fürst, Robert, Hoffmann, Florian, Khandoga, Alexander G., Krombach, Fritz, Mayer, Bettina A., Rehberg, Markus, Vollmar, Angelika M., Zahler, Stefan   +9 more
core   +1 more source

The Affinity of Histamine for Gq Protein-Coupled Histamine H1-Receptors Is Predominantly Regulated by Their Internalization in Human Astrocytoma Cells

Journal of Pharmacological Sciences, 2012
We examined the regulatory mechanisms of the affinity of Gq protein-coupled histamine H1-receptors for histamine after histamine pretreatment in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma, Yuko Sato, Chizuru Akatsu, Masaru Shoji   +3 more
doaj  

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

Brazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source

Population Pharmacokinetics of Fruquintinib, a Selective Oral Inhibitor of VEGFR ‐1, ‐2, and ‐3, in Patients with Refractory Metastatic Colorectal Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fruquintinib is a selective, oral tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors 1, 2, and 3, which is approved for patients with previously treated metastatic colorectal cancer regardless of biomarker status. This population pharmacokinetic (PK) analysis characterized sources of interpatient variability on
Xiaofei Zhou, Xiaoyan Yang, Boris Grinshpun, Adekemi Taylor, Laura Strong, Arvind Dasari, Andrea Wang‐Gillam, Jin Li, Rui‐Hua Xu, Neeraj Gupta, Caly Chien   +10 more
wiley   +1 more source

A Nanoporous Alumina Membrane Based Electrochemical Biosensor for Histamine Determination with Biofunctionalized Magnetic Nanoparticles Concentration and Signal Amplification

Sensors, 2016
Histamine is an indicator of food quality and indispensable in the efficient functioning of various physiological systems. Rapid and sensitive determination of histamine is urgently needed in food analysis and clinical diagnostics.
Weiwei Ye, Yifan Xu, Lihao Zheng, Yu Zhang, Mo Yang, Peilong Sun   +5 more
doaj   +1 more source

Critical mistakes in managing chronic constipation in the older person and how to avoid them: A narrative review

Journal of General and Family Medicine, EarlyView.
Abstract Objectives This narrative review identifies pitfalls in managing constipation in older adults and provides evidence‐based recommendations to avoid them. Methods A selective literature search was conducted across electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) to identify relevant publications on constipation management in ...
Madunil Niriella, Hiruni Jayasena, Prathibha Wijesingha, Janaka de Silva   +3 more
wiley   +1 more source

An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers

Journal of General and Family Medicine, EarlyView.
Abstract Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11‐month‐old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple ...
Takeru Kanazawa, Tomokazu Nakagami, Jyoji Yoshizawa, Yoshifusa Abe   +3 more
wiley   +1 more source