Results 61 to 70 of about 208,723 (221)

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission [PDF]

, 2016
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa.
A Musoke, A Musoke, AR Trimnell, AR Trimnell, AR Walker, AS Bowman, AS Young, AS Young, B Minjauw, C Almazán, C Almazán, C Almazán, C Almazán, CA Ferreira, Cassandra L. Olds, CL Schwartzkoff, Claudia Daubenberger, David O. Odongo, DO Odongo, DO Odongo, G Büscher, GC Paesen, GJ Rowlands, Glen A. Scoles, H Ochanda, I Couillin, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Katende, JD Hunt, JD Hunt, JG Valenzuela, JH Pruett, JM Ribeiro, JO Adejinmi, K Bailey, KM Kocan, M Labuda, M Saimo, M Shakya, MP Szabó, NA Steen, NH Ogden, O Merino, O Merino, P Willadsen, P Willadsen, P Willadsen, PG Toye, R Bishop, R Bishop, RA Skilton, RAI Norval, RC Galindo, Richard Bishop, S Havlíková, SK Wikel, Stephen Mwaura, T Bazarusanga, T Schetters, TT Dolan, V Nene, Z Zivkovic   +65 more
core   +3 more sources

O‐Terphenyl‐basierte Familie konjugierter Makrozyklen: Selektive Erkennung von Phenylalanin im Wasser und Interaktion mit Insulin

Angewandte Chemie, EarlyView.
Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

Histamine index and clinical expression of rheumatoid arthritis activity [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. Many arguments prove the pathophysiologic role of histamine in the process of remodeling and joint destruction in rheumatoid arthritis.
Tomić-Lučić Aleksandra P., Pantović Suzana B., Rosić Gvozden L., Obradović Zdravko M., Rosić Mirko A.   +4 more
doaj   +1 more source

Role of histaminegic and calcium channels in the inhibitory effects of hydroalcoholic extract of matricaria recutita L. on isolated rabbit jejunum [PDF]

, 2011
Introduction: Considering the long traditional history of anti-inflammatory and anti-spasmodic effects of Matricria spices on the gastrointestinal system, the present study aimed to investigate the role of calcium channels and Histamine receptors in the ...
Badaghabadi, F., Bayat, H., Hoseini, S.F., Khori, V., Mazandarani, M., Moheimani, H., Pourabouk, M., Rajaei, M., Seifi, A.   +8 more
core  

The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. [PDF]

, 2016
We tested the hypothesis that the anti-inflammatory actions of atrial natriuretic peptide (ANP) result from the modulation of leukocyte adhesion to inflamed endothelium and not solely ANP ligation of endothelial receptors to stabilize endothelial barrier
Adamson, Roger H, Clark, Joyce F, Curry, Fitz-Roy E, Jiang, Yanyan, Kim, Min-Ho, Simon, Scott I   +5 more
core   +2 more sources

o‐Terphenyl‐Based Family of Conjugated Macrocycles: Selective Recognition of Phenylalanine in Water and Interaction With Insulin

Angewandte Chemie International Edition, EarlyView.
This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule, Sayan Sarkar, Maria Eugenia Pérez‐Ojeda Rodriguez, Mark Spector, Frank Hampel, Evgeny A. Kataev   +5 more
wiley   +1 more source

気管支喘息の臨床分類とその細胞性および液性因子の特徴 [PDF]

, 1993
Characteristics of each asthma type classified by clinical symptoms and　findings were studied in 72 patients with bronchial asthma. 1. Ventilatory function tests showed that the values of % MMF, % V(50) and % V(25) were significantly lower in patients ...
Hiramatsu, Junichi, Kajimoto, Kazuhiro, Kawaraya, Masashi, Kimura, Ikuro, Kitani, Hikaru, Mifune, Takashi, Mitsunobu, Fumihiro, Nakagiri, Yoshiyasu, Sugimoto, Keisuke, Tada, Shinya, Tanizaki, Yoshiro, Yokota, Satoshi   +11 more
core   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Influence of mirtazapine on salivary cortisol in depressed patients [PDF]

, 2003
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C., Hennig, J., Laakmann, G., Schule, C.   +3 more
core   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source