Histamine H1 antagonists and clinical characteristics of febrile seizures. [PDF]
Int J Gen Med, 2012 Mohammed A ZolalyDepartment of Pediatrics, College of Medicine, Taibah University, Al-Madinah Al-Munawarah, Kingdom of Saudi ArabiaBackground: The purpose of this study was to determine whether seizure susceptibility due to antihistamines is provoked in ...
Zolaly MA.
europepmc +7 more sources
Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells [PDF]
Scientific Reports, 2021 Cancer therapy is often hampered by the disease’s development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is ...
Nobuki Matsumoto +5 more
doaj +3 more sources
Combination of H1 and H2 Histamine Receptor Antagonists: Current Knowledge and Perspectives of a Classic Treatment Strategy. [PDF]
Life (Basel)Histamine receptor antagonists, which can bind to specific histamine receptors on target cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated disorders.
Kou E, Zhang X, Dong B, Wang B, Zhu Y.
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Role and immunomodulatory profile of histamine receptors by H1 and H2 antagonists [PDF]
Nature Precedings, 2008 The present study was designed to delineate the immunomodulatory role of histamine receptors (H1- and H2-) on induction of antibody response to sheep red blood cells (SRBC), as well as the antibody generation profile, in rabbit system, systemically.
Mashiatullah Siddiqui +3 more
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Histamine H1 and H2 Receptor Antagonists Accelerate Skin Barrier Repair and Prevent Epidermal Hyperplasia Induced by Barrier Disruption in a Dry Environment [PDF]
, 2001 Keratinocytes have histamine H1 and H2 receptors, but their functions are poorly understood. To clarify the role of histamine receptors in the epidermis, we examined the effects of histamine receptor antagonists and agonists applied epicutaneously on the
Ashida, Yutaka +2 more
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Allergic Rhinoconjunctivitis: the Role of Histamine [PDF]
Mediators of Inflammation, 1994 Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
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Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H1 Receptor Blockade [PDF]
Frontiers in Psychiatry, 2012 Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics.
Kjell A Svensson
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Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells [PDF]
Scientific Reports, 2018 The histamine H1-receptor (H1R) is an important mediator of allergy and inflammation. H1R antagonists have particular clinical utility in allergic rhinitis and urticaria. Here we have developed six novel fluorescent probes for this receptor that are very
Leigh A. Stoddart +10 more
semanticscholar +2 more sources
Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in humans [PDF]
Journal of Translational Medicine, 2007 Background Medical implants often fail as a result of so-called foreign body reactions during which inflammatory cells are recruited to implant surfaces.
Eaton John W +2 more
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Allergology International, 2000 We have shown that some patients presenting with chronic bronchodilator-resistant non-productive cough have global atopic tendency, airway cough hyper-sensitivity without non-specific bronchial hyperresponsiveness and eosinophilic inflammation of the ...
Masaki Fujimura +4 more
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