Results 41 to 50 of about 35,308 (311)

Histamine and its Effects Mediated via H3 Receptor – Potential Clinical Applications of H3 Antagonists

open access: yesActa Medica Martiniana, 2013
Histamine is one of the most important biogenic amines and it mediates numbers of physiological processes. It is also involved in majority of inflammatory diseases via its receptors H1, H2, H3 and H4.
Hanuskova E., Plevkova J.
doaj   +1 more source

Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis. [PDF]

open access: yes, 2017
Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA).
Firestein, Gary S   +5 more
core   +1 more source

West Syndrome Associated with Administration of a Histamine H1 Antagonist, Oxatomide

open access: bronzeThe Kurume Medical Journal, 2004
We report a 4-month-old female infant who developed West syndrome eleven days after administration of a histamine H1 antagonist, oxatomide, for atopic dermatitis. It has been reported that some histamine H1 antagonists induce seizures in epileptic patients.
Yushiro Yamashita   +5 more
openalex   +5 more sources

The Histamine H4 Receptor: From Orphan to the Clinic

open access: yesFrontiers in Pharmacology, 2015
The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus ...
Robin L. Thurmond
doaj   +1 more source

The relation between antihistamine medication during early pregnancy & birth defects

open access: yesEgyptian Journal of Medical Human Genetics, 2015
Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H1 or H2). H1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.
Rabah M. Shawky, Neveen S. Seifeldin
doaj   +1 more source

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

open access: yes, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A.   +4 more
core   +2 more sources

Evaluation of the Histamine H1-Antagonist-Induced Place Preference in Rats

open access: yesJapanese Journal of Pharmacology, 1999
The place preferences by some histamine H1 antagonists, such as tripelennamine, optical isomers of chlorpheniramine (dl-, d- and l-forms) and pyrilamine, in rats were evaluated with the conditioned place preference paradigm. In the present study, tripelennamine and all of the optical isomers of chlorpheniramine, but not pyrilamine, produced a ...
Tsutomu Suzuki   +5 more
openaire   +2 more sources

Sites of action of sleep and wake drugs: insights from model organisms [PDF]

open access: yes, 2013
Small molecules have been used since antiquity to regulate our sleep. Despite the explosion of diverse drugs to treat problems of too much or too little sleep, the detailed mechanisms of action and especially the neuronal targets by which these compounds
Rihel, J, Schier, AF
core   +1 more source

Random Antagonistic Matrices [PDF]

open access: yesJ. Phys. A: Math. Theor. 49 (2016) 375601 (16pp), 2016
The ensemble of antagonistic matrices is introduced and studied. In antagonistic matrices the entries $\mathcal A_{i,j}$ and $\mathcal A_{j,i}$ are real and have opposite signs, or are both zero, and the diagonal is zero. This generalization of antisymmetric matrices is suggested by the linearized dynamics of competitive species in ecology.
arxiv   +1 more source

A Novel Membrane Sensor for Histamine H1-Receptor Antagonist “Fexofenadine”

open access: yesAnalytical Sciences, 2004
The construction and general performance of thirteen new polymeric membrane sensors for the determination of fexofenadine hydrochloride based on its ion exchange with reineckate, tetraphenylborate and tetraiodomercurate have been studied. The effects of membrane composition, type of plasticizer, pH value of sample solution and concentration of the ...
A. A. Abdel Fattah   +2 more
openaire   +4 more sources

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