Effects of Inhaled Brevetoxins in Allergic Airways: Toxin–Allergen Interactions and Pharmacologic Intervention [PDF]
During a Florida red tide, brevetoxins produced by the dinoflagellate Karenia brevis become aerosolized and cause airway symptoms in humans, especially in those with pre-existing airway disease (e.g., asthma).
Andrea J. Bourdelais+7 more
core +2 more sources
Deeply Virtual Compton Scattering at H1 and ZEUS [PDF]
Results on Deeply Virtual Compton Scattering at HERA measured by the H1 and ZEUS Collaborations are presented. The cross section, measured for the first time, is reported for by H1 and ZEUS for $Q^2$ above a few GeV$^2$ in the low $x$ region. The measured cross section is discussed and compared to different predictions.
arxiv +1 more source
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert+6 more
wiley +1 more source
Antihistamines in the treatment of allergic diseases: not as simple as it seems!
According to WHO, up to 35% of the world's population suffers from allergic diseases, and this number is growing exponentially. Histamine has been proven to play a key physiological role in the pathogenesis of allergic disorders by affecting tissues ...
Igor S. Guschin +2 more
doaj +1 more source
Analgesic effect of hystamine H2 receptor antagonists in formalin-induced pain model in rats [PDF]
JUSTIFICATIVA E OBJETIVOS: Antagonistas de receptor de histamina apresentam efeitos sobre a dor. Antagonistas de receptor H1 apresentam efeito analgésico local, o papel de antagonistas de receptor H2 sobre a dor no sistema nervoso periférico ainda não ...
ASHMAWI, Hazem Adel+3 more
core +1 more source
Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia+4 more
wiley +1 more source
Background: Allergic rhinitis is characterized by a chronic inflammation of nasal mucosa and represents a risk factor for asthma occurrence. H1 antihistamines reduce the symptoms of rhinitis, but some compounds may have anti-inflammatory properties ...
Corina I. Bocşan+5 more
doaj +1 more source
The effect of chronically intracerebroventricular injected histamine and its antagonists on the hypothalamic-pituitary-axis [PDF]
Merkezi sinir sistemi içerisinde nörotransmitter ve nöromodülatör etkiye sahip histamin, davranış durumunun, biyolojik ritmin, vücut ağırlığının, enerji metabolizmasının, termoregülasyonun, sıvı dengesinin, stresin ve üremenin düzenlenmesinde anahtar ...
Altınbaş, Burçin+1 more
core +1 more source
Emotional Contagion-Aware Deep Reinforcement Learning for Antagonistic Crowd Simulation [PDF]
The antagonistic behavior in the crowd usually exacerbates the seriousness of the situation in sudden riots, where the antagonistic emotional contagion and behavioral decision making play very important roles. However, the complex mechanism of antagonistic emotion influencing decision making, especially in the environment of sudden confrontation, has ...
arxiv
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt+5 more
wiley +1 more source