Results 121 to 130 of about 164 (159)
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Prebiotic synthesis of histidine
Journal of Molecular Evolution, 1990The prebiotic formation of histidine (His) has been accomplished experimentally by the reaction of erythrose with formamidine followed by a Strecker synthesis. In the first step of this reaction sequence, the formation of imidazole-4-acetaldehyde took place by the condensation of erythrose and formamidine, two compounds that are known to be formed ...
Stanley L. Miller +3 more
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Tetrahedron Letters, 2002
Abstract ( S )-3-Amino-4-[(1 H )imidazol-4-yl]butanoic acid ( 1 ), a β-amino acid which is a homologue of l -histidine, has been synthesised in five steps from l -histidine methyl ester. The presence of N (α)- and N (Im)-2,4,6-trimethylbenzenesulfonyl protecting groups was crucial to the success of the route, the key step of which involved the ...
Amit Kumar +3 more
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Abstract ( S )-3-Amino-4-[(1 H )imidazol-4-yl]butanoic acid ( 1 ), a β-amino acid which is a homologue of l -histidine, has been synthesised in five steps from l -histidine methyl ester. The presence of N (α)- and N (Im)-2,4,6-trimethylbenzenesulfonyl protecting groups was crucial to the success of the route, the key step of which involved the ...
Amit Kumar +3 more
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Polarity in the histidine operon
Journal of Molecular Biology, 1966Abstract Sixty-eight mutants in the C gene of the histidine operon in Salmonella typhimurium have been examined for polarity. All nonsense and frameshift mutants were found to be polar, whereas none of the missense mutants exhibited polarity. The mutants mapping on the side of the C cistron towards the operator region were more strongly polar ...
David F. Silbert +3 more
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Journal of Applied Chemistry, 1969
AbstractThe reactions of histidine were studied with the aim of converting this amino acid to 4‐vinylimidazole, but a commercially attractive scheme could not be developed.
K. Richardson, A. Hirsch
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AbstractThe reactions of histidine were studied with the aim of converting this amino acid to 4‐vinylimidazole, but a commercially attractive scheme could not be developed.
K. Richardson, A. Hirsch
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Nature, 1965
IT is well known that ultra-violet irradiation of proteins can cause changes of physiological importance but, despite the increasing number of publications on aspects of this problem, little is known of the primary processes which must precede or accompany the destruction of the macromolecule.
T. Jaskewycz, R.B. Johns
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IT is well known that ultra-violet irradiation of proteins can cause changes of physiological importance but, despite the increasing number of publications on aspects of this problem, little is known of the primary processes which must precede or accompany the destruction of the macromolecule.
T. Jaskewycz, R.B. Johns
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Inhibition of histidine decarboxylases
Life Sciences, 1963Abstract Histidine decarboxylases of mammalian origin are of two main types. One of these acts not only on histidine but also on other aromatic amino acids, notably L-3,4-dihydroxyphenylalanine (DOPA) and L-5-hydroxytryptophan. A typical example of this non-specific enzyme, for which the term aromatic L-amino acid decarboxylase has been suggested1 ...
D. M. Shepherd, Joan D. Reid
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Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005
Protein phosphorylation is one of the most ubiquitous and important types of post-translational modification for the regulation of cell function. The importance of two-component histidine kinases in bacteria, fungi and plants has long been recognised.
Paul V. Attwood, Paul G. Besant
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Protein phosphorylation is one of the most ubiquitous and important types of post-translational modification for the regulation of cell function. The importance of two-component histidine kinases in bacteria, fungi and plants has long been recognised.
Paul V. Attwood, Paul G. Besant
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Gastric histidine decarboxylase
Analytical Biochemistry, 1968Abstract A simple method is described for determining histidine decarboxylase activity. It depends on the measurement of 14 CO 2 liberated from tracer carboxyl- 14 C- l -histidine. The method is sensitive enough to permit measurements in small samples of gastric mucosa of individual rats. It is specific in that dopa decarboxylase does not interfere.
M. Ashwini Kumar, Phyllis E. Powell
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Selective Demonstration of Histidine
Stain Technology, 1956Mounted paraffin sections of formalin-fixed tissue are treated for 24 hr at room temperature in an iodine solution (0.3% iodine, 0.6% potassium iodide) at pH 10 to block the aromatic nuclei of tyrosine and tryptophane. A coupled tetrazonium reaction using naphthanil diazo blue B (tetrazotized o-dianisidine) as a 0.1% solution at pH 9.2 for 15 min at 4 ...
H E Hall, Benjamin H. Landing
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Histidine Decarboxylase and Growth
Nature, 1961KAHLSON1,2 has presented evidence of a relationship between activity of histidine decarboxylase and growth or wound-healing in rat tissues. In particular he has shown that the developing liver of the fœtal rat has much higher histidine decarboxylase activity than the normal liver of adults.
D. Mackay +3 more
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