Results 11 to 20 of about 228,380 (298)
Different Biological Activities of Histidine-Rich Peptides Are Favored by Variations in Their Design
Toxins, 2021 The protein transduction and antimicrobial activities of histidine-rich designer peptides were investigated as a function of their sequence and compared to gene transfection, lentivirus transduction and calcein release activities.
Morane Lointier +4 more
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Biosynthesis of Histidine [PDF]
EcoSal Plus, 2009 The biosynthesis of histidine in Escherichia coli and Salmonella typhimurium has been an important model system for the study of relationships between the flow of intermediates through a biosynthetic pathway and the control of the genes encoding the enzymes that catalyze the steps in a ...
Malcolm E. Winkler +1 more
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[Roles of Histidine Kinases and Histidine Phosphatases in Cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2021 Phosphorylation is the most common and important post-translational modification of proteins, which plays an important role in the regulation of cell proliferation, differentiation, development and metabolism, and is closely related to the tumorigenesis and metastasis of cancer.
Lili Guo +3 more
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Carboplatin binding to histidine [PDF]
Acta Crystallographica Section F Structural Biology Communications, 2014 Carboplatin is a second-generation platinum anticancer agent used for the treatment of a variety of cancers. Previous X-ray crystallographic studies of carboplatin binding to histidine (in hen egg-white lysozyme; HEWL) showed the partial conversion of carboplatin to cisplatin owing to the high NaCl concentration used in the crystallization conditions ...
Tanley, Simon W. M. +5 more
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Molecules, 2019 We previously reported on a polyhistidine peptide, His16 peptide, as a new cell-penetrating peptide. This peptide is anticipated to be a new carrier for drug delivery systems (DDSs) for targeting intracellular lysosomes because it can transport ...
Taiki Hayashi +3 more
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Journal of Fungi, 2020 Plant defensins are best known for their antifungal activity and contribution to the plant immune system. The defining feature of plant defensins is their three-dimensional structure known as the cysteine stabilized alpha-beta motif. This protein fold is
Mark R. Bleackley +8 more
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The Saudi Journal of Gastroenterology, 2017 Background/Aim: We investigated the association between blood amino acid concentration changes caused by elemental diet (ED) and their relationship to its therapeutic effect. Patients and Methods: Patients with active Crohn's disease (CD) followed ED for
Masakazu Nakano +5 more
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Fluorimetric Method for the Determination of Histidine in Random Human Urine Based on Zone Fluidics
Molecules, 2020 In the present study, the determination of histidine (HIS) by an on-line flow method based on the concept of zone fluidics is reported. HIS reacts fast with o-phthalaldehyde at a mildly basic medium (pH 7.5) and in the absence of additional nucleophilic ...
Antonios Alevridis +3 more
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Gut microbiota-derived metabolites in inflammatory diseases based on targeted metabolomics
Frontiers in Pharmacology, 2022 The gut microbiota plays an important role in inflammatory diseases. Metabolites in the three metabolic pathways of tryptophan (Trp), histidine (His), and phenylalanine (Phe) can affect various inflammatory conditions, such as obesity, diabetes ...
Hui Xu +12 more
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Biomimetics, 2019 Biology offers a valuable inspiration toward the development of self-healing engineering composites and polymers. In particular, chemical level design principles extracted from proteinaceous biopolymers, especially the mussel byssus, provide inspiration ...
Stefan Zechel +3 more
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