The sensor histidine kinase PhcS participates in the regulation of quorum sensing-dependent virulence genes in Ralstonia pseudosolanacearum strain OE1-1 [PDF]
Microbiology SpectrumRalstonia pseudosolanacearum strain OE1-1 secretes methyl 3-hydroxymyristate (3-OH MAME) as a quorum-sensing (QS) signal. Strain OE1-1 senses the chemical by the sensor histidine kinase PhcS, leading to the activation of the LysR family transcriptional ...
Wakana Senuma +7 more
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Diverse domain architectures of CheA histidine kinase, a central component of bacterial and archaeal chemosensory systems. [PDF]
Microbiol Spectr, 2023 Berry MA, Andrianova EP, Zhulin IB.
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The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains. [PDF]
J Biol ChemCho THS +8 more
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A Homolog of the Histidine Kinase RetS Controls the Synthesis of Alginates, PHB, Alkylresorcinols, and Motility in Azotobacter vinelandii. [PDF]
Curr MicrobiolRosales-Cruz A +6 more
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A Dual Regulatory Role of the PhoU Protein in Salmonella Typhimurium
mBio, 2022 Bacteria utilize two-component regulatory systems to sense and respond to their surroundings. Unlike other two-component systems that directly sense through a sensory domain in the histidine kinase (HK), the PhoB/PhoR two-component system requires ...
Soomin Choi +3 more
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Acid-Sensing Histidine Kinase With a Redox Switch
Frontiers in Microbiology, 2021 The EvgS/EvgA two-component signal transduction system in Escherichia coli is activated under mildly acidic pH conditions. Upon activation, this system induces the expression of a number of genes that confer acid resistance.
Shinya Inada +3 more
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Cell fate regulation governed by a repurposed bacterial histidine kinase. [PDF]
PLoS Biology, 2014 One of the simplest organisms to divide asymmetrically is the bacterium Caulobacter crescentus. The DivL pseudo-histidine kinase, positioned at one cell pole, regulates cell-fate by controlling the activation of the global transcription factor CtrA via ...
W Seth Childers +6 more
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Interaction of vitamin D, homocystein and dental diseases
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 The 1,2,4-triazole nucleus is resistant to metabolism and is an important pharmacophore; it can increase solubility and improve the pharmacokinetic and pharmacodynamic profile of drugs.
Ye. O. Karpun +3 more
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Interaction Analysis of a Two-Component System Using Nanodiscs. [PDF]
PLoS ONE, 2016 Two-component systems are the major means by which bacteria couple adaptation to environmental changes. All utilize a phosphorylation cascade from a histidine kinase to a response regulator, and some also employ an accessory protein.
Patrick Hörnschemeyer +4 more
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Visualizing autophosphorylation in histidine kinases [PDF]
Nature Communications, 2014 Reversible protein phosphorylation is the most widespread regulatory mechanism in signal transduction. Autophosphorylation in a dimeric sensor histidine kinase is the first step in two-component signalling, the predominant signal-transduction device in bacteria.
Casino, Patricia +2 more
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