Results 1 to 10 of about 111,385 (294)

Antigenic peptide binding by class I and class II histocompatibility proteins [PDF]

open access: yesStructure, 1994
The recent determination of the structure of a class II MHC molecule complexed to a specific peptide reveals both similarities and differences with peptide binding by class I MHC.
L J, Stern, D C, Wiley
openaire   +3 more sources

Minors come of age: minor histocompatibility antigens and graft-versus-host disease [PDF]

open access: yes, 2004
Minor histocompatibility antigens (miHA) are responsible for the occurrence of graft-versus-host disease in the setting of a major histocompatibility complex matched sibling allogeneic stem cell transplantation.
Chao, Nelson J
core   +1 more source

Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA [PDF]

open access: yes, 1986
Transformation of murine thymocytes by radiation leukemia virus is associated with reduced expression of the class I antigens encoded in the major histocompatibility complex (MHC) and increased methylation and altered restriction enzyme patterns of MHC ...
Boral, Anthony   +11 more
core   +1 more source

Structure and function of major histocompatibility complex class I antigens [PDF]

open access: yesCurrent Opinion in Organ Transplantation, 2010
Major histocompatibility complex (MHC) class I molecules control the repertoire and function of CD8 T cells and NK cells, and both cell types are involved in transplant rejection. Understanding the regulatory role of MHC class I molecules is important in the design of better therapies.
Xian C, Li, Malini, Raghavan
openaire   +2 more sources

Recognition of major histocompatibility complex antigens on cultured human biliary epithelial cells by alloreactive lymphocytes [PDF]

open access: yes, 1991
We have developed an in vitro system to study the interactions between biliary epithelium and lymphocytes using cultured human biliary epithelial cells.
Demetris, AJ   +5 more
core   +1 more source

Differential phosphorylation of murine class I major histocompatibility antigens

open access: yesBioscience Reports, 1988
Recent studies have shown that the H-2K and H-2D transplantation antigens are expressed differentially in different tissues of mouse. Our previous investigations also established that in thioglycolate-stimulated peritoneal macrophages the H-2Dk antigen exists in distinct cell surface and intracellular forms. These two forms are glycosylated differently.
W J, Hong, A, Van Le, D, Doyle
openaire   +2 more sources

Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]

open access: yes, 2018
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar   +7 more
core   +6 more sources

Antigen-induced suppression: The role of Class I major histocompatibility antigens

open access: yesBioscience Reports, 1985
The role of Class I major histocompatibility (MHC) antigens in the induction of specific suppression of graft rejection has been investigated. Two experimental transplantation models have been used ’ fully vascularized heterotopic Cardiac altografts in the mouse and fully vascularized orthotopic renal allografts in the rat.
K J, Wood, P J, Morris
openaire   +2 more sources

Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]

open access: yes, 1989
Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Engler-Blum, G.   +5 more
core   +1 more source

Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers. [PDF]

open access: yes, 2020
The study objective was to test the hypothesis that having histocompatible children increases the risk of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), possibly by contributing to the persistence of fetal cells acquired during ...
Barcellos, Lisa F   +16 more
core  

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