Results 11 to 20 of about 115,135 (343)

Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran ...
Fatemeh Toghani Hulari   +4 more
doaj   +1 more source

Antigenic peptide binding by class I and class II histocompatibility proteins [PDF]

open access: yesStructure, 1994
The recent determination of the structure of a class II MHC molecule complexed to a specific peptide reveals both similarities and differences with peptide binding by class I MHC.
L J, Stern, D C, Wiley
openaire   +3 more sources

The MHC class I MICA gene is a histocompatibility antigen in kidney transplantation

open access: yesNature Medicine, 2022
AbstractThe identity of histocompatibility loci, besides human leukocyte antigen (HLA), remains elusive. The major histocompatibility complex (MHC) class I MICA gene is a candidate histocompatibility locus. Here, we investigate its role in a French multicenter cohort of 1,356 kidney transplants.
Carapito, Raphael   +40 more
openaire   +5 more sources

Structure and function of major histocompatibility complex class I antigens [PDF]

open access: yesCurrent Opinion in Organ Transplantation, 2010
Major histocompatibility complex (MHC) class I molecules control the repertoire and function of CD8 T cells and NK cells, and both cell types are involved in transplant rejection. Understanding the regulatory role of MHC class I molecules is important in the design of better therapies.
Xian C, Li, Malini, Raghavan
openaire   +2 more sources

Homotypic and heterotypic in cis associations of MHC class I molecules at the cell surface

open access: yesCurrent Research in Immunology, 2022
Through the presentation of peptide antigens to cytotoxic T lymphocytes, major histocompatibility complex (MHC) class I molecules mediate the adaptive immune response against tumors and viruses.
Fernando M. Ruggiero, Sebastian Springer
doaj   +1 more source

Recognition of major histocompatibility complex antigens on cultured human biliary epithelial cells by alloreactive lymphocytes [PDF]

open access: yes, 1991
We have developed an in vitro system to study the interactions between biliary epithelium and lymphocytes using cultured human biliary epithelial cells.
Demetris, AJ   +5 more
core   +1 more source

Antigen-induced suppression: The role of Class I major histocompatibility antigens

open access: yesBioscience Reports, 1985
The role of Class I major histocompatibility (MHC) antigens in the induction of specific suppression of graft rejection has been investigated. Two experimental transplantation models have been used ’ fully vascularized heterotopic Cardiac altografts in the mouse and fully vascularized orthotopic renal allografts in the rat.
K J, Wood, P J, Morris
openaire   +2 more sources

Major histocompatibility class I antigens in the Lebanese population

open access: yesEastern Mediterranean Health Journal, 2021
Except for two reports on Lebanese immigrants, there have been no studies on the major histocompatibility [MHC] antigens in the Lebanese population. We describe the frequency and distribution of MHC class I antigens present in the A, B and C loci based on data obtained from 200 healthy unrelated individuals from different parts of Lebanon.
N. N. Salti, M. Shaya
openaire   +1 more source

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

open access: yeseLife, 2018
Devil Facial Tumour 2 (DFT2) is a recently discovered contagious cancer circulating in the Tasmanian devil (Sarcophilus harrisii), a species which already harbours a more widespread contagious cancer, Devil Facial Tumour 1 (DFT1).
Alison Caldwell   +13 more
doaj   +1 more source

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