Results 11 to 20 of about 64,134 (148)

Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells. [PDF]

PLoS ONE, 2010
BACKGROUND: Major histocompatibility complex (MHC) antigens are important for alloimmune responses as well as immune tolerance. Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon ...
Shuzi Zhang, Hehua Dai, Ni Wan, Yolonda Moore, Zhenhua Dai   +4 more
doaj   +1 more source

Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran ...
Fatemeh Toghani Hulari, Mozhgan Esmaili, Mohammad Akbari, Fatemeh Khajenabi, Saeid Abediankenari   +4 more
doaj  

Dendritic cells crosspresent antigens from live B16 cells more efficiently than from apoptotic cells and protect from melanoma in a therapeutic model. [PDF]

PLoS ONE, 2011
Dendritic cells (DC) are able to elicit anti-tumoral CD8(+) T cell responses by cross-presenting exogenous antigens in association with major histocompatibility complex (MHC) class I molecules.
Diana Matheoud, Camille Baey, Lene Vimeux, Andy Tempez, Michael Valente, Pauline Louche, Agnès Le Bon, Anne Hosmalin, Vincent Feuillet   +8 more
doaj   +1 more source

Escape from the phagosome: the explanation for MHC-I processing of mycobacterial antigens?

Frontiers in Immunology, 2012
Mycobacterium tuberculosis (Mtb) is thought to live in an altered phagosomal environment. In this setting, the mechanisms by which mycobacterial antigens access the major histocompatibility class I (MHC-I) processing machinery remain incompletely ...
Melanie eHarriff, Melanie eHarriff, Georgiana ePurdy, David M Lewinsohn, David M Lewinsohn, David M Lewinsohn   +5 more
doaj   +1 more source

Serum Levels of Classical HLA Class I Antigen in HIV-Infected patients during antiretroviral therapy. Correlation with the clinical outcome

Journal of Biological Research, 2009
Aim. Human major histocompatibility complex class I antigens (HLA-A, -B, and -C) are heterodimetric molecules composed of a heavy chain non covalently associated with an invariant protein known as B2-microglobulin. Besides being expressed on the membrane
G. Murdaca, P. Cagnati, F. Puppo
doaj   +1 more source

Structure and function of major histocompatibility complex class I antigens [PDF]

Current Opinion in Organ Transplantation, 2010
Major histocompatibility complex (MHC) class I molecules control the repertoire and function of CD8 T cells and NK cells, and both cell types are involved in transplant rejection. Understanding the regulatory role of MHC class I molecules is important in the design of better therapies.
Xian C, Li, Malini, Raghavan
openaire   +2 more sources

Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex

Emerging Infectious Diseases, 1997
Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj   +1 more source

Differential phosphorylation of murine class I major histocompatibility antigens

Bioscience Reports, 1988
Recent studies have shown that the H-2K and H-2D transplantation antigens are expressed differentially in different tissues of mouse. Our previous investigations also established that in thioglycolate-stimulated peritoneal macrophages the H-2Dk antigen exists in distinct cell surface and intracellular forms. These two forms are glycosylated differently.
W J, Hong, A, Van Le, D, Doyle
openaire   +2 more sources

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

Antigen-induced suppression: The role of Class I major histocompatibility antigens

Bioscience Reports, 1985
The role of Class I major histocompatibility (MHC) antigens in the induction of specific suppression of graft rejection has been investigated. Two experimental transplantation models have been used ’ fully vascularized heterotopic Cardiac altografts in the mouse and fully vascularized orthotopic renal allografts in the rat.
K J, Wood, P J, Morris
openaire   +2 more sources