Results 101 to 110 of about 108,384 (342)

HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen

BMC Genetics, 2004
Background The main genomic region controlling the predisposition to type 1 diabetes is the Human Leukocyte Antigens (HLA) class II of the major histocompatibility complex. Association with different HLA types depends also on the studied populations.
Aribi Mourad, Moulessehoul Soraya, Benabadji Ahmed-Bakir, Kendoucitani Mohammed   +3 more
doaj   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

Angewandte Chemie, EarlyView.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito, Yoshiyuki Manabe, Shino Ohshima, Masatoshi Maeki, Manabu Tokeshi, Hiroshi Inaba, Kazunori Matsuura, Kazuya Kabayama, Yoshie Kametani, Koichi Fukase   +9 more
wiley   +2 more sources

The human leukocyte antigen system … simplified

Global Journal of Transfusion Medicine, 2017
Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
doaj   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

Advanced Science, EarlyView.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li, Fulong Man, Jianwei Cheng, Li Chen, Yongyong Li, Haiqing Dong   +5 more
wiley   +1 more source

Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions [PDF]

, 2010
The goal of cancer vaccines is to induce antitumor immunity that ultimately will reduce tumor burden in tumor environment. Several strategies involving dendritic cells- (DCs)- based vaccine incorporating different tumor-associated antigens to induce ...
Gong, Jianlin, Hara, Eiichi, Homma, Sadamu, Ito, Masaki, Koido, Shigeo, Komita, Hideo, Nagasaki, Eijiro, Namiki, Yoshihisa, Ohkusa, Toshifumi, Tajiri, Hisao, Takahara, Akitaka   +10 more
core   +4 more sources

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Frecuencia fenotípica y génica de los antígenos HLA en una muestra de la población cubana Phenotypic and genic frequency of HLA antigens in a sample of the Cuban population

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2005
Se realizó un estudio de la frecuencia fenotípica y génica de los antígenos del sistema principal de histocompatibilidad HLA en personas no relacionadas, supuestamente sanas, tomadas como muestra de la población cubana.
Luz M Morera Barrios, Catalino R, Ustáriz García, María A. García García, Nelioska Díaz Báez, Rosa M Lam Díaz, Ana M Guerreiro Hernández, Porfirio Hernández Ramírez, José M Ballester Santovenia   +8 more
doaj  

PREVALENCE OF POLYMORPHIC VARIANTS OF GENES HLA SYSTEM IN HEALTHY DONORS OF KRASNODAR REGION

Кубанский научный медицинский вестник, 2017
Polymorphism studies major histocompatibility complex human (HLA-system) in the world, held from mid-60s, when serotyping methods revealed that in different populations are determined by different sets of options HLA-antigens.
A. I. Tlif, E. I. Kondratyeva, N. V. Tarasenko, М. Ya. Zobenko, A. A. T. Kodenev, L. R. Gysaryk   +5 more
doaj   +1 more source

Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells. [PDF]

, 1988
Christine W. Czarniecki, Hsien Hung Chiu, G H Wong, Susan McCabe, Michael A. Palladino   +4 more
openalex   +1 more source