Results 231 to 240 of about 108,384 (342)

Research progress in the application of single‐cell sequencing technology in rheumatic diseases

Rheumatology &Autoimmunity, EarlyView.
Application of single‐cell RNA sequencing (scRNA‐seq) technology in the study of the pathogenesis of rheumatic diseases. Tree of content illustration depicting the multi‐layered insights from scRNA‐seq in rheumatic diseases. The outer layer highlights key cell subsets identified by scRNA‐seq in rheumatoid arthritis, systemic lupus erythematosus ...
Xinzhe Feng, Zhou Ji, Changhao Han, Zhi Li, Chenxu Liu, Weidong Xu   +5 more
wiley   +1 more source

Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature. [PDF]

World J Transplant
Jiang SM, Li XJ, Wang ZL, Chen ZW, Liu ZL, Li Q, Chen XL.   +6 more
europepmc   +1 more source

The use of MHC class I or class II 'knock out' mice to investigate the role of these antigens in allosensitization [PDF]

, 1995
Demetris, AJ, Fu, F, Fung, JJ, Gao, L, Li, Y, Lu, L, Noyola, H, Qian, S, Rao, AS, Starzl, TE, Thomson, AW   +10 more
core  

MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-ASSOCIATED VACCINE PROTECTION FROM SIMIAN IMMUNODEFICIENCY VIRUS-INFECTED PERIPHERAL-BLOOD CELLS [PDF]

, 1994
Boes, J, Bontrop, RE, Cranage, M, de Vries, P, Dings, M, Dubbes, R, Heeney, JL, Jonker, M, Koornstra, W, Niphuis, H, Norley, S, Osterhaus, A, Otting, N, ten Haaft, P, van Els, C   +14 more
core   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Swine Xenografts Share Few Predicted Indirectly Recognisable SLA-Derived Epitopes With HLA-Derived Epitopes From Human Kidney Grafts. [PDF]

HLA
Matern BM, Spierings E, Peereboom E, Tector M, Tector J, Mangiola M, Montgomery RA, Niemann M.   +7 more
europepmc   +1 more source

Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3

, 2017
Yong‐Chen Lu, Linda L. Parker, Tangying Lu, Zhili Zheng, Mary Ann Toomey, Donald E. White, Xin Yao, Yong F. Li, Paul F. Robbins, Steven A. Feldman, Pierre van der Bruggen, Christopher A. Klebanoff, Stephanie L. Goff, Richard M. Sherry, Udai S. Kammula, James C. Yang, Steven A. Rosenberg   +16 more
openalex   +2 more sources

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Allogeneic NKG2D CAR-T Cell Therapy: A Promising Approach for Treating Solid Tumors. [PDF]

Biomedicines
Mukhametshin SA, Gilyazova EM, Davletshin DR, Ganeeva IA, Zmievskaya EA, Chasov VV, Petukhov AV, Valiullina AK, Spada S, Bulatov ER.   +9 more
europepmc   +1 more source

Regulatory T Cells and Nanomaterials: Dual Perspectives in Therapeutics and Immunomodulation

Small Science, EarlyView.
Tregs control immune tolerance but can also enable tumor escape. Nanomaterials can now expand or stabilize Tregs to treat autoimmunity and support transplantation or conversely disrupt tumor Tregs to boost antitumor immunity. We also discuss unintended Treg modulation by nanoparticles, safety and manufacturing challenges, and future translational ...
Yiyin Chen, Haibo Huang, Xiang Wang, Xinghao Yu, Ziyan Huang, Zhou Jin, Chen Chen, Yan Chen, Bruce R. Blazar, Yang Xu, Yunjie Lu   +10 more
wiley   +1 more source