Results 51 to 60 of about 453,877 (390)

Resting Porcine T Lymphocytes Expressing Class II Major Histocompatibility Antigen

Immunobiology, 1991
The immune system of swine is unique in that the expression of CD4 and CD8 antigens defines four subpopulations of resting, extrathymic (CD1-) T lymphocytes in the circulation as well as in lymphoid tissue. Here it is documented that the specialty of the porcine T lymphocyte compartment extends to the expression of class II MHC (SLA) antigens.
Frank Weiland, Armin Saalmüller, Matthias J. Reddehase   +2 more
openaire   +3 more sources

Expression of MHC class II antigens by conjunctival epithelial cells in trachoma: implications concerning the pathogenesis of blinding disease. [PDF]

, 1991
In an attempt to understand the pathogenesis of corneal changes and conjunctival scarring in trachoma, which are responsible for blindness in some 7 million people worldwide, the surface expression of major histocompatibility complex class II antigens on
D C Mabey, D Dunn, D Jones, H C Whittle, J H Williams, M E Ward, R L Bailey   +6 more
core   +1 more source

PCR-based isolation of multigene families: Lessons from the avian MHC class IIB [PDF]

, 2013
The amount of sequence data available today highly facilitates the access to genes from many gene families. Universal primers amplifying the desired genes over a range of species are readily obtained by aligning conserved gene regions, and laborious gene isolation procedures can often be replaced by quicker PCR-based approaches.
arxiv   +1 more source

The Class II Major Histocompatibility Complex Antigen Deficiency Syndrome: Consequences of Absent Class II Major Histocompatibility Antigens for Lymphocyte Differentiation and Function

Journal of Investigative Dermatology, 1990
The class II major histocompatibility complex antigen deficiency syndrome is a rare immunodeficiency disease associated with defective expression of the class II antigens encoded for by the major histocompatibility complex. Clinically, this syndrome is manifest as a combined immunodeficiency presenting early in life, and affected individuals are ...
openaire   +3 more sources

Trypanosoma brucei brucei infection impairs MHC class II antigen presentation capacity of macrophages

, 2000
During African trypanosomiasis, macrophages play a central role in T cell hyporesponsiveness to parasite-related and unrelated antigens. In this study, the ability of macrophages from Trypanosoma b. brucei-infected mice to present exogenous antigens to a
Beschin, A, Brys, L, De Baetselier, P, Magez, Stefan, Namangala, B   +4 more
core   +2 more sources

Major histocompatibility class II peptide occupancy, antigen presentation, and CD4+ T cell function in mice lacking the p41 isoform of invariant chain [PDF]

, 1995
We used a “hit and run” gene targeting strategy to generate mice expressing only the p31 isoform of the conserved invariant (li) chain associated with major histocompatibility complex (MHC) class II molecules.
Norma T. Takaesu, Jennifer A. Lower, Elizabeth J. Robertson, Elizabeth K. Bikoff, Amigorena, Anderson, Anderson, Arunachalam, Avva, Baake, Bertolino, Bhattacharya, Bijlmakers, Bijlmakers, Bikoff, Bikoff, Bikoff, Bikoff, Bikoff, Bodmer, Bonnerot, Busch, Castellino, Chicz, Collins, Cosgrove, Cresswell, Dornmair, Elliott, Fierz, Freisewinkel, Germain, Germain, Glimcher, Grusby, Hämmerling, Hasty, Hedley, Hugo, Janeway, Janeway, Jaraquemada, Kampgen, Koch, Koch, Koch, Kvist, Lamb, Layet, Loss, Lotteau, Machamer, Malnati, Mehringer, Miller, Momburg, Momburg, Momburg, Nadimi, Neefjes, Nijenhuis, Nuchtern, O'Sullivan, Ozato, Peterson, Peterson, Pinet, Pober, Polla, Pujol-Borrell, Pujol-Borrell, Ramirez-Solis, Roche, Roche, Roche, Roche, Roehm, Romagnoli, Romagnoli, Sadegh-Nasseri, Sant, Schaiff, Sekaly, Sette, Stern, Stockinger, Strubin, Sung, Teyton, Tulp, Van Kaer, Vidal, Viville, Zhu   +93 more
core   +1 more source

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

Journal of Experimental Medicine, 1991
Interleukin 10 (IL-10) and viral IL-10 (v-IL-10) strongly reduced antigen-specific proliferation of human T cells and CD4+ T cell clones when monocytes were used as antigen-presenting cells.
R. D. Malefyt, J. Haanen, H. Spits, M. Roncarolo, A. Velde, C. Figdor, K. E. Johnson, R. Kastelein, H. Yssel, J. D. Vries   +9 more
semanticscholar   +1 more source

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Cell Reports, 2021
Summary: Intestinal epithelial cells (IECs) have long been understood to express high levels of major histocompatibility complex class II (MHC class II) molecules but are not considered canonical antigen-presenting cells, and the impact of IEC-MHC class ...
W. Zac Stephens, Jason L. Kubinak, Arevik Ghazaryan, Kaylyn M. Bauer, Rickesha Bell, Kate Buhrke, Tyson R. Chiaro, Allison M. Weis, William W. Tang, Josh K. Monts, Ray Soto, H. Atakan Ekiz, Ryan M. O’Connell, June L. Round   +13 more
doaj  

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens*

Journal of Biological Chemistry, 2012
Background: Dectin-1 is a phagocytic receptor important for host immune responses to fungal infections. Results: Dectin-1 signaling directs LC3 to phagosomes leading to increased MHC class II recruitment and increased presentation of fungal-derived ...
Jun Ma, Courtney A. Becker, C. Lowell, D. Underhill   +3 more
semanticscholar   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source